Results 51 to 60 of about 68,214 (292)

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Exit, punishment and rewards in commons dilemmas: an experimental study. [PDF]

PLoS ONE, 2013
Commons dilemmas are interaction situations where a common good is provided or exploited by a group of individuals so that optimal collective outcomes clash with private interests.
Giangiacomo Bravo, Flaminio Squazzoni
doaj   +1 more source

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

EX-UTERO INTRAPARTUM TREATMENT (EXIT)

Revista Médica Clínica Las Condes, 2021
Resumen: El ex-utero intrapartum treatment (EXIT) es una estrategia de parto que permite brindar soporte cardiopulmonar al feto con el objetivo de realizar una intervención vital durante la transición a la vida extrauterina.
María Florencia Varela, Jose L. Peiro
doaj   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Entrepreneurial Exit: Research Perspectives and Challenges

Problemy Zarządzania, 2016
The objective of this paper is to characterize selected dimensions of the phenomenon of entrepreneurial exit from the perspective of strategies other than succession in a family business.
Izabela Koładkiewicz, Marta Wojtyra
doaj   +1 more source

key questions for modelling covid 19 exit strategies covid 19 exit strategies

Proceedings of The Royal Society B: Biological Sciences, 2020
Combinations of intense non-pharmaceutical interventions (lockdowns) were introduced worldwide to reduce SARS-CoV-2 transmission. Many governments have begun to implement exit strategies that relax restrictions while attempting to control the risk of a surge in cases.
Kris V Parag, Matthew James Keeling, Trevelyan J. McKinley, A. Philip Dawid, Olivier Restif, Juliet R. C. Pulliam, Nigel Gilbert, Robin N Thompson, Robin N Thompson, Emma S. McBryde, Christl A. Donnelly, Alun L. Lloyd, Joshua V. Ross, Claudio J. Struchiner, Joel C. Miller, Hannah E. Clapham, James M. McCaw, Denis Mollison, Daniel Arribas-Bel, Pieter Trapman, Hans Heesterbeek, Istvan Z. Kiss, Tom Britton, Gianpaolo Scalia Tomba, Michael J. Tildesley, Nik J. Cunniffe, Martina Morris, Lorenzo Pellis, Rosalind M Eggo, Ben Ashby, William S Hart, Thomas House, Paul Glendinning, T. Déirdre Hollingsworth, Philip D. O'Neill, Julia R. Gog, Sebastian Funk, Valerie Isham, Bernard W. Silverman, Lauren H. K. Chappell, Cerian R. Webb, Peter Challenor, Mirjam Kretzschmar, Carl A. B. Pearson   +43 more
openaire   +4 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source