Results 301 to 310 of about 207,257 (328)

Genetic variants linked to type 2 diabetes in CDKN1B and TCF7L2 influence survival outcomes in metastatic colorectal cancer

International Journal of Cancer, EarlyView.
What's New? Multiple genetic polymorphisms characteristic of type 2 diabetes (T2D) have been associated with unfavorable prognostic outcomes in individuals with both T2D and metastatic colorectal cancer. This study evaluated the impact of T2D genetic polymorphisms on metastatic colon cancer prognosis in a cohort of non‐diabetic patients.
Raffaella Ruggiero, Alessandro Ottaiano, Madhura Tathode, Roberto Sirica, Annabella Di Mauro, Monica Ianniello, Nadia Petrillo, Massimiliano Berretta, Silvia Zappavigna, Amalia Luce, Michele Caraglia, Giovanni Savarese   +11 more
wiley   +1 more source

Exome sequencing of UK birth cohorts. [PDF]

Wellcome Open Res
Koko M, Fabian L, Popov I, Eberhardt RY, Zakharov G, Huang QQ, Wade EE, Azad R, Danecek P, Ho K, Hough A, Huang W, Lindsay SJ, Malawsky DS, Bonfanti D, Mason D, Plowman D, Quail MA, Ring SM, Shireby G, Widaa S, Fitzsimons E, Iyer V, Bann D, Timpson NJ, Wright J, Hurles ME, Martin HC.   +27 more
europepmc   +1 more source

Gut microbiota and tuberculosis

iMeta, EarlyView.
This review explores the intricate relationship between gut microbiota (GM) and tuberculosis (TB). The figure illustrates the bidirectional effects between GM dynamics and TB progression, as well as the interactions between the GM and antituberculosis drugs.
Yanhua Liu, Ling Yang, Maryam Meskini, Anjana Goel, Monique Opperman, Sagar Singh Shyamal, Ajay Manaithiya, Meng Xiao, Ruizi Ni, Yajing An, Mingming Zhang, Yuan Tian, Shuang Zhou, Zhaoyang Ye, Li Zhuang, Linsheng Li, Istuti Saraswat, Ankita Kar, Syed Luqman Ali, Shakir Ullah, Syed Yasir Ali, Shradha Kaushik, Tianmu Tian, Mingyang Jiao, Shujun Wang, Giulia Ghisleni, Alice Armanni, Sara Fumagalli, WenYu Wang, Chao Cao, Maria Carpena, Miguel A. Prieto, Antonia Bruno, Chanyuan Jin, Hanqing Hu, Yuhang Zhang, Ilse du Preez, Ashok Aspatwar, Lingxia Zhang, Wenping Gong   +39 more
wiley   +1 more source

Identification of a rare variant in TNNT3 responsible for familial dilated cardiomyopathy through whole-exome sequencing and in silico analysis. [PDF]

Eur J Med Res
Jadidi M, Babaali V, InanlooRahatloo K, Salehi N, Mollazadeh R.   +4 more
europepmc   +1 more source

Patient‐derived xenograft models in pan‐cancer: From bench to clinic

Interdisciplinary Medicine, EarlyView.
Abstract Patient‐derived xenograft (PDX) models provide a robust preclinical platform that preserves the genetic and phenotypic heterogeneity of patient tumors while mirroring their tumor genetic characteristics, which retain malignant cells and the tumor pathological structure, making them valuable for studying tumor progression and developing ...
Jiatong Li, Ao Gu, Nannan Tang, Gokhan Zengin, Meng‐Yao Li, Yingbin Liu   +5 more
wiley   +1 more source

Whole-Exome Sequencing: Discovering Genetic Causes of Granulomatous Mastitis. [PDF]

Int J Mol Sci
Ozcinar B, Ocak Z, Billur D, Ertugrul B, Timirci-Kahraman O.   +4 more
europepmc   +1 more source

Trio whole exome sequencing in Chinese childhood-onset lupus reveals novel candidate genes. [PDF]

Arthritis Rheumatol
Ma J, Qin Y, Hong SM, Ware T, Hou G, Tan J, Xie C, Zhang P, Wu X, Arsov T, Cao L, Andrews TD, Wu P, Shen Q, Ding H, Shen N, Vinuesa CG, He Y.   +17 more
europepmc   +1 more source

Mechanisms of tumor heterogeneity in TACE-resistant liver cancer: Insights from single-cell and whole-exome sequencing. [PDF]

Hepatol Commun
Liu J, Zhang Y, Ran W, Yang L, Zhang W, Liu Z.   +5 more
europepmc   +1 more source

Revisiting the molecular landscape of Rosai-Dorfman disease: insights from whole exome sequencing of Saudi patients. [PDF]

Front Oncol
Binhassan S, Samman M, Al-Sheikh Y, Alshakweer W, Alhalouli T, Alshamlan N, Abudawood M.   +6 more
europepmc   +1 more source

Clinical and genetic findings in autism spectrum disorders analyzed using exome sequencing. [PDF]

Front Psychiatry
Blázquez A, Rodriguez-Revenga L, Alvarez-Mora MI, Calvo R.   +3 more
europepmc   +1 more source