Results 251 to 260 of about 586,929 (366)

Exon mapping by PCR [PDF]

Nucleic Acids Research, 1993
L, Niu, G F, Crouse
openaire   +2 more sources

Exon level integration of proteomics and microarray data [PDF]

, 2008
Danny A. Bitton, Michał Okoniewski, Yvonne Connolly, Crispin Miller   +3 more
openalex   +1 more source

SV2B Promotes the Progression of TFE3‐Rearranged Renal Cell Carcinoma by Interacting with HERC2 to Impede the Degradation of NF‐κB Subunits

Advanced Science, EarlyView.
TFE3‐rearranged renal cell carcinoma (TFE3‐RCC) lacks clearly defined diagnostic and therapeutic targets. SV2B, a TFE3 target gene, promotes TFE3‐RCC progression by activating the NF‐κB pathway. Targeted inhibition with padsevonil or Withaferin A effectively suppresses tumor progression.
Huayi Feng, Zhuang Xiong, Shaoqing Yu, Junxiao Liu, Shouqing Cao, Kan Liu, Xing Huang, Lequan Wen, Baojun Wang, Qingbo Huang, Tiejun Pan, Xu Zhang, Xin Ma, Xiubin Li   +13 more
wiley   +1 more source

Exploring exon excision as a therapeutic intervention strategy for the future treatment of <i>ADGRV1-</i>associated retinitis pigmentosa. [PDF]

Mol Ther Nucleic Acids
Stemerdink M, Malinar L, Broekman S, Peters T, Ensink I, Ivanchenko MV, Venselaar H, Kremer H, de Vrieze E, van Wijk E.   +9 more
europepmc   +1 more source

HTGTS‐TCR‐Seq for Profiling of Mouse and Human T‐Cell Receptor α and β Gene Rearrangements and Diversity

Advanced Science, EarlyView.
HTGTS‐TCR‐seq is an efficient and cost‐effective method for profiling TCRα and TCRβ rearrangements using only a few primers. It captures both productive and nonproductive recombination events, minimizes primer bias, and reveals stage‐specific and age‐related repertoire changes in mice, as well as conserved features in human peripheral T cells ...
Rui Luo, Yawei Song, Meichen Wang, Longhao Zou, Fangtai Jiao, Tiange Yang, Guangchuan Wang, Zhuoyi Liang, Wei Wu, Hai‐Qiang Dai   +9 more
wiley   +1 more source

Analysis of cfDNA fragmentomics metrics and commercial targeted sequencing panels. [PDF]

Nat Commun
Helzer KT, Sharifi MN, Sperger JM, Chrostek MR, Bootsma ML, Reese SR, Taylor A, Kaufmann KR, Krause H, Schehr J, Sethakorn N, Kosoff D, Kyriakopoulos CE, Bassetti M, Blitzer G, Floberg J, Sjöström M, Armstrong AJ, Beltran H, McKay RR, Feng FY, O'Regan R, Wisinski KB, Emamekhoo H, Wyatt AW, Lang JM, Zhao SG.   +26 more
europepmc   +1 more source

Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells.

Journal of Clinical Investigation, 1997
I. Shimomura, H. Shimano, J. Horton, J. Goldstein, Michael S. Brown   +4 more
semanticscholar   +1 more source

Biased exon/intron distribution of cryptic and de novo 3' splice sites [PDF]

, 2005
Jana Královičová, Mikkel Christensen, Igor Vořechovský   +2 more
openalex   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

Chimeric RNA isoforms generated by diverse mechanisms from two C-type lectins modulate innate immunity in arthropods. [PDF]

Proc Natl Acad Sci U S A
Huang Y, Huang X, Zhang LH, Ren Q.
europepmc   +1 more source