Nonsense mutations inhibit splicing of MVM RNA in cis when they interrupt the reading frame of either exon of the final spliced product. [PDF]
Lisa K. Naeger+4 more
openalex +1 more source
A model is schematically represented for the major molecular mechanisms by which homocysteine (Hcy) accelerates the nuclear export of circ‐PIAS1‐5, which regulates atherosclerosis by acting as a competing endogenous RNA for miR‐219a‐2‐3p. Hcy enrichment of circ‐PIAS1‐5 leads to YTHDC1 binding to circ‐PIAS1‐5 and promotes its intracellular localization ...
Shengchao Ma+13 more
wiley +1 more source
Refining the annotation of <i>Rhodnius prolixus</i> aspartic proteases A1 family genes through proteogenomics. [PDF]
Ouali R, Bousbata S.
europepmc +1 more source
Association with terminal exons in pre-mRNAs: a new role for the U1 snRNP? [PDF]
Karen M. Wassarman, Joan A. Steitz
openalex +1 more source
Enhancer eccANKRD28‐manipulated MM cells have been demonstrated to facilitate drug resistance and promote MM progression by activating the key transcription factor, POU2F2. POU2F2 interacts with sequence‐specific eccANKRD28 as well as RUNX1 and RUNX2 motifs to form the protein complex, which activates the promoter of oncogenes (IRF4, JUNB, IKZF3, et al.
Binzhen Chen+12 more
wiley +1 more source
Antisense oligonucleotides modulate aberrant inclusion of poison exons in SCN1A-related Dravet syndrome. [PDF]
Tang S+4 more
europepmc +1 more source
Exons 1–10 of the Rat LH Receptor Encode a High Affinity Hormone Binding Site and Exon 11 Encodes G-Protein Modulation and a Potential Second Hormone Binding Site [PDF]
Inhae Ji, Tae H. Ji
openalex +1 more source
This study uncovers the activation, heterogeneity, and regulatory roles of pancreatic stellate cells (PSCs) at single‐cell and spatial levels. It further identifies PLXDC1+ PSCs near aggressive LRRC15+ cancer‐associated myofibroblasts and SPP1+ macrophages, forming a desmoplastic and immunosuppressive tumor niche that promotes CD8+ T cell exhaustion ...
Yanhua Du+12 more
wiley +1 more source
Discovery of circular transcripts of the human BCL2-like 12 (BCL2L12) apoptosis-related gene, using targeted nanopore sequencing, provides new insights into circular RNA biology. [PDF]
Karousi P+5 more
europepmc +1 more source