Results 341 to 350 of about 586,929 (366)

Exons as enhancers

Nature Reviews Genetics, 2019
A study in Cell identifies a mechanism by which exon splicing can increase gene expression through the activation of weak upstream promoters.
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The universe of exons revisited

Genetica, 2003
We study the distribution of exons in eukaryotic genes to determine whether one can detect the reuse of exon sequences and to use the frequency of such reuse to estimate how many ancestral exon sequences there might have been. We use two databases of exons.
Serge, Saxonov, Walter, Gilbert
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exon

2023
exon
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Exons and the evolution of proteins

Trends in Biochemical Sciences, 1983
Publisher Summary This chapter discusses exons and evolution of proteins. The splitting of most eukaryotic structural genes into coding sequences (exons) and noncoding sequences (introns) is widely interpreted in terms of evolutionary processes concerned with the gene products.
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Influence of Exon Duplication on Intron and Exon Phase Distribution

Journal of Molecular Evolution, 1998
Nonrandomness in the intron and exon phase distributions in a sample of 305 human genes has been found and analyzed. It was shown that exon duplications had a significant effect on the exon phase nonrandomness. All of the nonrandomness is probably due to both the processes of exon duplication and shuffling.
A, Fedorov, L, Fedorova, V, Starshenko, V, Filatov, E, Grigor'ev   +4 more
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Isolation of Exons from Cloned DNA by Exon Trapping

Current Protocols in Human Genetics, 1994
AbstractExon trapping is an RNA polymerase chain reaction (PCR) method to clone expressed sequences or exons directly from mammalian genomic DNA. The basic protocol in this unit describes the method for trapping internal exons from cosmid clones and the second basic protocol describes trapping of 3 terminal exons.
P E, Nisson, P C, Watkins, D B, Krizman
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Exons as Microgenes?

Science, 1992
H M, Seidel, D L, Pompliano, J R, Knowles   +2 more
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Exon–exon junction – what's your function?

Trends in Cell Biology, 2001
The expression of aberrant proteins can have disastrous consequences for a cell. Quality-control mechanisms that survey newly synthesized mRNAs are therefore essential to cellular well being. Unspliced pre-mRNAs are retained in the nucleus because they fail to associate with the appropriate export factors.
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Exon

2006
  +6 more sources

Exon

2011
  +6 more sources