Results 51 to 60 of about 1,979 (168)

Exploring Pelvic Changes: Do Pregnancy and Birth Leave Scars?

open access: yesAmerican Journal of Biological Anthropology, Volume 189, Issue 4, April 2026.
ABSTRACT Objectives Selected pelvic features, formerly “parturition scars,” have long been interpreted as osteological indicators of pregnancy and childbirth, presumably caused by biomechanical stresses. Yet, most evidence derives from archaeological collections lacking detailed documented reproductive histories.
Anja Catic   +11 more
wiley   +1 more source

Hereditary multiple exostoses: an educational review

open access: yesInsights into Imaging
Hereditary multiple exostoses (HME), an autosomal dominant disorder with an incidence of 1:50,000 to 1:100,000, is characterised by the formation of multiple osteochondromas arising from the metaphyses of long and flat bones.
Alvaro Rueda-de-Eusebio   +5 more
doaj   +1 more source

Orthopedic preoperative evaluation and surgical strategies of hereditary multiple osteochondromas involving the spinal region

open access: yesEFORT Open Reviews
Hereditary multiple osteochondromas (HMO), previously known as hereditary multiple exostoses (HME), is a congenital skeletal developmental anomaly characterized by multiple osteochondromas that commonly grow outward from the metaphyses of long bones ...
Shuzhong Liu   +4 more
doaj   +1 more source

Knuckle, Knuckle, Dimple, Dimple: Do Not Miss A Diagnostic Opportunity

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
Archibald's metacarpal sign is characterized by dimpling over the knuckles when the fist is clenched, resulting from relative shortening of the fourth and fifth metacarpals compared with the third. ABSTRACT Turner syndrome (TS) often presents with subtle or overlooked clinical signs, contributing to frequent diagnostic delays. We describe the case of a
Maria Chiara Pellegrin   +4 more
wiley   +1 more source

Solitary Metacarpal Osteochondroma; an Unusual Location

open access: yesMedicine Science, 2014
Although, osteochondroma is the most common bone tumor, metacarpal involvement is quite uncommon and usually accompanies multiple hereditary exostoses.
Aziz Atik   +4 more
doaj   +1 more source

Presence of IDH2 and TP53 mutations significantly reduces survival of patients with chondrosarcoma

open access: yesCancer, Volume 132, Issue 7, 1 April 2026.
Abstract Background Chondrosarcoma (CS) has a prognosis largely influenced by tumor grade. Although IDH mutations have been reported in CS, impact on patient`s survival remains controversial. This study aims to assess prognostic relevance of IDH mutations on disease‐specific survival (DSS), metastasis‐free survival (MFS), and local recurrence‐free ...
Anne Weidlich   +8 more
wiley   +1 more source

The Extracellular Matrix Across States: From Homeostasis to Dysfunction in Rare Connective Tissue Disorders

open access: yesProteoglycan Research, Volume 4, Issue 2, April 2026.
ABSTRACT The extracellular matrix (ECM) provides a dynamic environment in which the fine balance between biosynthesis, degradation and/or maturation of matrix components critically governs its structure and function. It is well established that the ECM plays a central role not only in the physiological functions of tissues, but also in the pathogenesis
Roméo M. Diana   +2 more
wiley   +1 more source

Do plantar calcaneal spurs make the plantar aponeurosis enthesis stronger? A biomechanical analysis

open access: yesJournal of Anatomy, Volume 248, Issue 4, Page 591-597, April 2026.
Novel testing set up for determining enthesial avulsion parameters. Donor calcanei were dissected to isolate the central band of the plantar fascia, and mounted in a custom 3D‐printed rig (Fig A, B, C) for uniaxial tensile testing of the plantar fascia enthesis (Fig D). This study demonstrated no significant differences in the avulsion parameters, Fmax
Joanna Tomlinson   +2 more
wiley   +1 more source

Pathogenesis and potential therapeutic targets of trichorhinophalangeal syndrome; lessons obtained from animal studies

open access: yesDevelopmental Dynamics, Volume 255, Issue 3, Page 228-245, March 2026.
Abstract Trichorhinophalangeal syndrome (TRPS) is a rare genetic disease inherited in an autosomal dominant manner. It occurs in 1 in 100,000 people globally and is caused by several types of mutations of the TRPS1 gene. Since the first human patient was reported in 1966, typical and atypical pathologies, disease courses, and treatment case ...
Naoya Saeki   +6 more
wiley   +1 more source

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