Novel antimicrobial peptides that inhibit gram positive bacterial exotoxin synthesis. [PDF]
PLoS ONE, 2014 Gram-positive bacteria, such as Staphylococcus aureus, cause serious human illnesses through combinations of surface virulence factors and secretion of exotoxins. Our prior studies using the protein synthesis inhibitor clindamycin and signal transduction
Joseph A Merriman +2 more
doaj +1 more source
Phase I clinical study of the recombinant antibody toxin scFv(FRP5)-ETA specific for the ErbB2/HER2 receptor in patients with advanced solid malignomas [PDF]
, 2005 Introduction: ScFv(FRP5)-ETA is a recombinant antibody toxin with binding specificity for ErbB2 (HER2). It consists of an N-terminal single-chain antibody fragment (scFv), genetically linked to truncated Pseudomonas exotoxin A (ETA).
Gunter von Minckwitz +49 more
core +1 more source
"Alternative" endocytic mechanisms exploited by pathogens: new avenues for therapeutic delivery? [PDF]
, 2007 Some pathogens utilize unique routes to enter cells that may evade the intracellular barriers encountered by the typical clathrin-mediated endocytic pathway.
Medina-Kauwe, LK
core +1 more source
Syntaxin 16 and syntaxin 5 are required for efficient retrograde transport of several exogenous and endogenous cargo proteins [PDF]
, 2007 Retrograde transport allows proteins and lipids to leave the endocytic pathway to reach other intracellular compartments, such as trans-Golgi network (TGN)/Golgi membranes, the endoplasmic reticulum and, in some instances, the cytosol. Here, we have used
Amessou, Mohamed +7 more
core +1 more source
Ciencias Marinas, 2003 The pathogenicity of two V. penaeicida strains, AM101 and KH-1, with different geographic origin, and V. nigripulchritudo strain AM102, were investigated in juvenile blue shrimp species Litopenaeus stylirostris.
G Aguirre-Guzmán +6 more
doaj +1 more source
Incidence and Characteristics of Scarlet Fever, South Korea, 2008–2015
Emerging Infectious Diseases, 2017 The incidence rate for scarlet fever in South Korea is rising. During 2008–2015, we collected group A Streptococcus isolates and performed emm and exotoxin genotyping and disk-diffusion antimicrobial tests.
Duck Woong Park +15 more
doaj +1 more source
Jurnal Entomologi Indonesia, 2016 The aim of this experiment was to find out the type of medium that was potential for the metabolite production and growth of P. luminescens. LB, NB, Wakimoto, and T3 were examined as growth media for metabolite production and growth of P. luminescens. LB
Wartono Wartono, Tri Puji Priatno
doaj +1 more source
Screening for staphylococcal superantigen genes shows no correlation with the presence or the severity of chronic rhinosinusitis and nasal polyposis. [PDF]
PLoS ONE, 2010 BACKGROUND: Staphylococcus aureus secretes numerous exotoxins which may exhibit superantigenic properties. Whereas the virulence of several of them is well documented, their exact biological effects are not fully understood.
Frédéric Heymans +14 more
doaj +1 more source
Clonal complexes and diversity of exotoxin gene profiles in methicillin-resistant and methicillin-susceptible Staphylococcus aureus isolates from patients in a Spanish hospital [PDF]
, 2009 This work was supported by project FIS-06-PI052489 from the Spanish Ministry of Science and Innovation and projects BfR 45-004 and 45-005 of the Federal Institute for Risk Assessment (BfR), Germany. M.A.Argudín is the recipient of grant FPU AP 2004-3641
Argudín Regueiro, María Ángeles +5 more
core +1 more source
Development and validation of an ELISA to detect antibodies to Corynebacterium pseudotuberculosis in ovine sera [PDF]
, 2007 Several enzyme-linked immunosorbent assays (ELISAs) have been developed for the detection of antibodies to Corynebacterium pseudotuberculosis, the causative agent of caseous lymphadenitis (CLA). However, none are commercially available in the UK.
Bailey, Mick +2 more
core +5 more sources