Results 71 to 80 of about 12,606 (114)

Anthrax protective antigen is a calcium-dependent serine protease

Virulence, 2018
Bacillus anthracis secretes a three component exotoxin-complex, which contributes to anthrax pathogenesis. Formation of this complex starts with the binding of protective antigen (PA) to its cellular receptor.
Lisanne Storm, Floris J. Bikker, Kamran Nazmi, Albert G. Hulst, Debora V. der Riet-Van Oeveren, Enno C.I. Veerman, John P. Hays, Wendy E. Kaman   +7 more
doaj   +1 more source

Molecular detection of virulence factors and biofilm formation in Pseudomonas aeruginosa obtained from different clinical specimens in Bandar Abbas

Iranian Journal of Microbiology, 2019
Background and Objectives: Pseudomonas aeruginosa is a ubiquitous opportunistic pathogen. The presence of several virulence factors such as exotoxin and exoenzyme genes and biofilm may contribute to its pathogenicity.
Nima Bahador, Saeed Shoja, Foroogh Faridi, Banafsheh Dozandeh-Mobarrez, Fatemeh Izadpanah Qeshmi, Sedigheh Javadpour, Sedigheh Mokhtary   +6 more
doaj   +1 more source

Challenging the Clostridium botulinum toxin type A (BoNT/A) with a selection of microorganisms by culture methods and extended storage of used vials to assess the loss of sterility [PDF]

, 2015
In 2002, botulinum toxin type A (BoNT/A) was approved by the US Food and Drug Administration (FDA) for cosmetic use. However, there may be procedural differences between the ways in which a clinician handles, applies and stores the product compared to ...
Crean, Stjohn, Dennison, Sarah Rachel, Morton, Leslie Hugh Glyn, Singhrao, Simarjit Kaur, Turner, Martin   +4 more
core  

Necrotizing Pneumonia Caused by PVL‐Negative Methicillin‐Susceptible Staphylococcus aureus Complicated by Refractory Pneumothorax: A Case Report

Respirology Case Reports, Volume 14, Issue 1, January 2026.
Here we report a case of PVL‐negative MSSA necrotizing pneumonia in a previously healthy man that rapidly progressed to cavitary lesions and refractory pneumothorax. Despite its improvement after clindamycin‐based therapy, the patient experienced recurrent pneumothorax and chronic respiratory failure.
Shun Endo, Tomoka Yasuda, Makoto Izumi, Kazuhiro Shimaya, Yoshikazu Tsukada   +4 more
wiley   +1 more source

Considerations and challenges of septic arthritis and osteomyelitis

Equine Veterinary Education, Volume 38, Issue 1, Page 19-25, January 2026.
Summary Septic arthritis remains a common orthopaedic condition in both human and veterinary medicine which can cause serious morbidity and pose considerable challenges for clinical management. The majority of the published clinical research in humans and veterinary species has been focused on the diagnosis, treatment, prevention and outcome of this ...
J. B. Engiles, H. L. Stewart
wiley   +1 more source

The Immunomodulatory Effect of Recombinant Exotoxin A of Pseudomonas Aeruginosa on Dendritic Cells Extracted from Mice Spleen [PDF]

Journal of Advanced Biomedical Sciences, 2014
Background & Objective: Dendritic cell (DC) is as a key cell in activation of immune response against microbes and disease. Therefore, the effect of recombinant exotoxin A of Pseudomonas aeruginosa on the maturity and the activation of DCs was evaluated ...
Mohammad Hossein Karimi, Aziz Japoni, Manouchehr Rasouli, Salimeh Ebrahimnezhad   +3 more
doaj  

Progress of Programmed Cell Death in Steroid‐Induced Osteonecrosis of the Femoral Head

Orthopaedic Surgery, Volume 18, Issue 1, Page 16-30, January 2026.
Steroid‐induced osteonecrosis of the femoral head is a severe osteoarticular condition resulting from glucocorticoid overuse, characterized by femoral head bone structure collapse and cell death, now predominant among nontraumatic femoral head necroses.
Zhi Kong, Chao Han
wiley   +1 more source

How to rewire the host cell: A home improvement guide for intracellular bacteria. [PDF]

, 2017
Intracellular bacterial pathogens have developed versatile strategies to generate niches inside the eukaryotic cells that allow them to survive and proliferate.
Cornejo, Elias, Mukherjee, Shaeri, Schlaermann, Philipp   +2 more
core   +2 more sources

Structural Characterization and Functional Annotation of Hypothetical Proteins in the Multidrug‐Resistant Strains of Pseudomonas aeruginosa

BioMed Research International, Volume 2026, Issue 1, 2026.
Introduction Pseudomonas aeruginosa is a leading cause of severe nosocomial infections worldwide. This opportunistic pathogen is associated with increased morbidity and mortality rates due to its high levels of antibiotic resistance. The identification of novel therapeutic targets is therefore a pressing global health priority.
Fatemeh Nasiri Khoonsari, Zahra Zafari, Bufu Tang   +2 more
wiley   +1 more source

Beta‐Thalassemia Major Complicated by Streptococcal Toxic Shock Syndrome: A Rare Case of Survival and Successful Management

Case Reports in Hematology, Volume 2026, Issue 1, 2026.
Beta‐thalassemia is an inherited blood disorder associated with defective hemoglobin production and impaired immunity, increasing susceptibility to severe infections. Streptococcus pyogenes poses a significant risk due to its potential to cause streptococcal toxic shock syndrome (STSS), a life‐threatening condition characterized by fever, shock, and ...
Fajr Saeedi, Masaheer A. Aljehani, Suraiya Saleem   +2 more
wiley   +1 more source