Results 61 to 70 of about 1,365,472 (249)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Beyond the Book project: quantitative data and collateral documents for One Book, One Chicago [PDF]
, 2008 Quantitative data and collateral documents Chicago portion of the AHRC-funded project ‘Beyond the Book: Mass Reading Events and Contemporary Cultures of Reading in the UK, USA and Canada’, (2005-2008, grant number: 112166), a three-year interdisciplinary
Engel, Lindsay +3 more
core +2 more sources
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Expériences sensibles de la ville.
EspacesTemps.net, 2009 De quelle manière nos jugements esthétiques, politiques et moraux s’ancrent-ils dans ― ou interfèrent-ils avec ― notre expérience sensible de la ville ?
Vinh Dao
doaj
Sensualité des expériences mystiques chez Augustin [PDF]
, 2014 Dans ses Confessions, long discours qu’il adresse directement à Dieu, Augustin explique comment l’homme, inquiet de s’être détourné de Dieu par insouciance, aspire intérieurement à retourner à son créateur, et à vivre l’expérience de plénitude associée à
Côté, Robert
core +2 more sources
Motivating Students by Active Learning in the History Classroom [PDF]
, 2020 The highest challenge we face as classroom teachers is to motivate our students to love history as we do, and to be joyously involved with the texts, themes, issues, and questions of history that interest and excite us.
Frederick, Peter J.
core +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Les Entreprises Minières Chinoises au Katanga République Démocratique du Congo [PDF]
, 2009 The article speaks about the Chinese mining enterprise in Katanga observe by NGO ...
Jean-Pierre Okenda +2 more
core