An electronic, unsupervised patient-reported Expanded Disability Status Scale for multiple sclerosis. [PDF]
Mult Scler, 2021 Background: In persons with multiple sclerosis (MS), the Expanded Disability Status Scale (EDSS) is the criterion standard for assessing disability, but its in-person nature constrains patient participation in research and clinical assessments. Objective: The aim of this study was to develop and validate a scalable, electronic, unsupervised patient ...
Romeo AR +15 more
europepmc +8 more sources
Validation of a machine learning approach to estimate expanded disability status scale scores for multiple sclerosis. [PDF]
Mult Scler J Exp Transl Clin, 2022 Background Disability assessment using the Expanded Disability Status Scale (EDSS) is important to inform treatment decisions and monitor the progression of multiple sclerosis. Yet, EDSS scores are documented infrequently in electronic medical records.
Alves P +6 more
europepmc +5 more sources
Disability status and quality of life in multiple sclerosis: non-linearity of the Expanded Disability Status Scale (EDSS) [PDF]
Health and Quality of Life Outcomes, 2010 Background Progression in disability as measured by increase in the Expanded Disability Status Scale (EDSS) is commonly used as outcome variable in clinical trials concerning multiple sclerosis (MS).
Pöhlau Dieter +7 more
doaj +7 more sources
A comparative analysis of Patient-Reported Expanded Disability Status Scale tools. [PDF]
Mult Scler, 2016 Background: Patient-Reported Expanded Disability Status Scale (PREDSS) tools are an attractive alternative to the Expanded Disability Status Scale (EDSS) during long term or geographically challenging studies, or in pressured clinical service environments.
Collins CD +8 more
europepmc +9 more sources
Association between Expanded Disability Status Scale score and dietary antioxidant capacity in patients with multiple sclerosis [PDF]
Brazilian Journal of Medical and Biological Research, 2023 Multiple sclerosis (MS), a neuroinflammation that results in neurodegeneration, is the most prevalent central nervous system inflammatory disease in young people.
S. Mungan, I. Guzel, B.C. Demirdogen
doaj +4 more sources
The Expanded Disability Status Scale Score and Demographic Indexes Are Correlated with the Severity of Cognitive Impairment in Multiple Sclerosis Patients. [PDF]
J Clin Neurol, 2021 Background and Purpose Cognitive impairment (CI) is a common symptom of multiple sclerosis (MS). Although demographic and clinical factors contribute to MS-dependent CI, previous findings have been inconsistent. This study aimed to identify the cognitive
Sadigh-Eteghad S +3 more
europepmc +3 more sources
Expanded Disability Status Scale (EDSS) in Multiple Sclerosis
Cam & Sakura Medical Journal, 2022 Multiple sclerosis has an increasing prevalence and incidence. There are many articles showing that early treatment can prevent possible disability. Expanded disability status scale assessmenthas great importance both in pivotal studies and in clinical ...
Serkan Demir
doaj +3 more sources
Int J Prev Med, 2021 Background: Multiple sclerosis (MS) is an inflammatory disease while there are controversies regarding the role of vitamin D supplements in controlling relapse and disability improvement during treatment. Objective: The goal of this systematic review and
Hanaei S +4 more
europepmc +3 more sources
Brain Function Assessment of Patients with Multiple Sclerosis in the Expanded Disability Status Scale: A Proposal for Modification. [PDF]
Int J MS Care, 2020 Abstract Background: There is no consensus regarding assessment of the brain function functional system (FS) of the Expanded Disability Status Scale (EDSS) in patients with multiple sclerosis (MS). We sought to describe brain function FS assessment criteria used by Argentinian neurologists and, based ...
Alonso RN +7 more
europepmc +4 more sources
Application of Item Response Theory to Modeling of Expanded Disability Status Scale in Multiple Sclerosis [PDF]
The AAPS Journal, 2016 In this study, we report the development of the first item response theory (IRT) model within a pharmacometrics framework to characterize the disease progression in multiple sclerosis (MS), as measured by Expanded Disability Status Score (EDSS). Data were collected quarterly from a 96-week phase III clinical study by a blinder rater, involving 104,206 ...
A. Novakovic +4 more
semanticscholar +6 more sources