Results 41 to 50 of about 39,999 (178)

Immune Soluble Factors in the Cerebrospinal Fluid of Progressive Multiple Sclerosis Patients Segregate Into Two Groups

Frontiers in Immunology, 2021
Primary-progressive (PP) and secondary-progressive (SP) multiple sclerosis (MS) are characterized by neurological deficits caused by a permanent neuronal damage, clinically quantified by the expanded disability status scale (EDSS). Neuronal tissue damage
Gloria Donninelli, Valeria Studer, Valeria Studer, Laura Brambilla, Chiara Zecca, Chiara Zecca, Daniele Peluso, Alice Laroni, Alice Laroni, Daniele Michelis, Renato Mantegazza, Paolo Confalonieri, Elisabetta Volpe   +12 more
doaj   +1 more source

Natural History of Early Onset Multiple Sclerosis

Pediatric Neurology Briefs, 2002
The clinical course of multiple sclerosis (MS) in 116 patients with onset before age 16 (prevalence 3.6% in total MS clinic attendees) was evaluated by longitudinal study (mean duration 19.76 +/- 0.9 years) at the University of British Columbia MS Clinic.
J Gordon Millichap
doaj   +1 more source

Factors influencing the degree of disability in patients with neuromyelitis optica spectrum disorders

European Journal of Medical Research, 2023
Objective To investigate the factors influencing the degree of disability in patients with neuromyelitis optica spectrum disorder (NMOSD) and provide evidence for disease monitoring and clinical intervention.
Lili Shi, Dawei Li, Yunxiu Zhang, Jinling Wang, Jingxuan Fu, Xia Liu, Peichang Wang   +6 more
doaj   +1 more source

Oligoclonal Band Status and Features of Radiological and Clinical Findings in Patients with Multiple Sclerosis in Lithuania

Medicina, 2023
Background and Objectives: Multiple sclerosis (MS) is a widely spread and debilitating disease with 2.8 million people worldwide currently affected.
Emilija Aleksandravičiūtė, Radvilė Stankevičiūtė, Renata Balnytė, Laurynas Šaknys, Ingrida Ulozienė   +4 more
doaj   +1 more source

Serum level of brain-derived neurotrophic factor in patients with relapsing–remitting multiple sclerosis: a potential biomarker for disease activity

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2021
Background Brain-derived neurotrophic factor (BDNF) is secreted by immune cells in response to neuroimmune and inflammatory cascades as an act to prevent axonal and neuronal damage after various pathological insults. The serum level of BDNF is altered in
Mohammed I. Oraby, Hatem A. El Masry, Sanaa S. Abd El Shafy, Esraa M. Abdul Galil   +3 more
doaj   +1 more source

Natural course of multiple sclerosis in the first five years of the disease in the Kujawsko-Pomorskie district

Aktualności Neurologiczne, 2016
Aim: The aim of the study was to emphasize the prognostic value of the first five years of the natural course of multiple sclerosis for the disability progression, and a comparison of the relapsing-remitting and the primary progressive disease course ...
Łukasz Rzepiński, Sławomir Wawrzyniak, Małgorzata Rzepińska   +2 more
doaj   +1 more source

Design and Validation of an Expanded Disability Status Scale Model in Multiple Sclerosis

European Neurology, 2021
<b><i>Introduction:</i></b> We aimed to develop and validate an Expanded Disability Status Scale (EDSS) model through clinical, optical coherence tomography (OCT), and magnetic resonance imaging (MRI) measures. <b><i>Methods:</i></b> Sixty-four multiple sclerosis (MS) patients underwent peripapillary ...
Barreiro-Gonzalez, Antonio, Sanz, Maria T., Carratala-Bosca, Sara, Perez-Miralles, Francisco, Alcala, Carmen, Carreres-Polo, Joan, España-Gregori E, Casanova, Bonaventura   +7 more
openaire   +3 more sources

Apelin-13: A promising biomarker for multiple sclerosis?

Annals of Indian Academy of Neurology, 2018
Objectives: Recent studies have shown that Apelin 13 may have a neuroprotective property. Therefore it can be used as a biomarker for multiple sclerosis.
Murat Alpua, Yakup Turkel, Ersel Dag, Ucler Kisa   +3 more
doaj   +1 more source

Historical and Clinical Perspectives of the Expanded Disability Status Scale [PDF]

Neuroepidemiology, 2008
<i>Background:</i> The measurement of neurologic impairment in multiple sclerosis (MS) is of importance in treatment trials and course of illness. <i>Methods:</i> This review describes the rationale underlying the formation and use of a bifid rating system, the (Expanded) Disability Status Scale (DSS) and the Functional Systems (
openaire   +2 more sources

Physical therapy for a patient with neuromyelitis optica during the acute phase: A case report

SAGE Open Medical Case Reports, 2021
The aim of this report was to examine the safety of physical therapy for hemiplegia in a patient with neuromyelitis optica in the acute phase. A 32-year-old female with neuromyelitis optica diagnosed by magnetic resonance imaging had a T2-weighted ...
Yuichi Nishikawa, Noriaki Maeda, Hiroaki Kimura   +2 more
doaj   +1 more source