dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Developing a novel immobilization method for breast cancer radiation therapy with tissue expander. [PDF]
Czubowicz A, Szczyrek Z, Senkowska M.
europepmc +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
CO₂ Refrigeration at Very Low Temperatures Using Natural Gas Expansion
The pressure reduction of natural gas in distribution networks generally leads to a significant loss of available energy due to the use of throttling valves.
Malek HAMZAOUI +2 more
doaj
Prefabricated Expanded Skin Flap With the Serratus Branch of the Thoracodorsal Artery for Extensive Facial Resurfacing. [PDF]
Li K +7 more
europepmc +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Serially Stacked Acellular Dermal Matrices in 2-Stage Implant-Based Breast Reconstruction. [PDF]
Yom J, Smith IT, Odoom GP, Tanna N.
europepmc +1 more source
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
Pain Experience During Rapid Maxillary Expansion: A Prospective Observational Study. [PDF]
De Stefani A +4 more
europepmc +1 more source

