Worklife Expectancy and Disability in the Forensic Arena: A Response to Chapter 20 “Worklife Expectancy Models and Concepts” in Rick Robinson’s Foundations of Forensic Vocational Rehabilitation [PDF]
Enrique N. Vega, Joseph T. Crouse
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Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
When the cure leaks: corruption, health spending, and health outcomes in Malawi. [PDF]
Front Public HealthYusufu EG, Bangara BC, Banda LG.
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How Geography, Race and Ethnicity Affect Life Expectancy at 50: New Jersey State Level Analysis
, 2023 Erwin J. Tan +2 more
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Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Neural Reinstatement of Encoding Context Mediates the Switch between Fear and Extinction Recall. [PDF]
J Cogn NeurosciHennings AC +3 more
europepmc +1 more source
Bystander Intervention in Cyberbullying and Online Harassment: The Role of Expectancy Violations
, 2021 Nicholas Brody
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Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
The Link Between Life Expectancy, Infant Mortality Rate and Health Expenditure: A Global Perspective
Srishti Ray, Reshmi Ganguly
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