Results 291 to 300 of about 536,569 (368)

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei   +7 more
wiley   +1 more source

Restoring life expectancy in low-income countries: the combined impact of COVID-19, health expenditure, GDP, and child mortality. [PDF]

open access: yesBMC Public Health
Karunarathne M   +5 more
europepmc   +1 more source

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

open access: yesFEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren   +8 more
wiley   +1 more source

Critical Illness, Major Surgery, and Other Hospitalizations and Active and Disabled Life Expectancy.

open access: yesJAMA Netw Open
Gill TM   +6 more
europepmc   +1 more source

Disease Burden of 30 Cancer Groups in Taiwan from 2000 to 2021. [PDF]

open access: yesJ Epidemiol Glob Health
Liu PC   +7 more
europepmc   +1 more source

Comparative study of adenosine 3′‐pyrophosphokinase domains of MuF polymorphic toxins

open access: yesFEBS Open Bio, EarlyView.
With the ultimate goal of understanding the association of toxin‐immunity modules to temperate phages, we characterized toxins from three prophages and examined cross‐protection from immunity proteins. The toxins exhibit adenosine 3′‐pyrophosphokinase activity and are toxic in Escherichia coli.
Eloïse M. Paulet   +6 more
wiley   +1 more source

The impact of non-pharmaceutical interventions on COVID-19 transmission and its effect on life expectancy in two European regions. [PDF]

open access: yesBMC Public Health
Estadilla CDS   +9 more
europepmc   +1 more source

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