Results 41 to 50 of about 269,922 (244)
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
In 1 John, the author refers several times explicitly to himself (also once in the plural, 1:4) for writing (γράφειν) certain things with the following purposes in mind, (that, ἵνα): ‘our joy may be complete’ (1:4); ‘you may not sin’ (2:1); and ‘you may ...
Dirk G. van der Merwe
doaj +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Background and objectiveThe psychological mechanisms that make Conditioned Pain Modulation (CPM) an effective non-pharmacological intervention are still not fully understood.
Xueshan Li +5 more
doaj +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Student motivational profiles and self-regulated learning strategies are significant influences on overall academic success in university settings. Test anxiety has been repeatedly linked to maladaptive learning strategies and ineffective motivational ...
Jerrell C. Cassady, W. Holmes Finch
doaj +1 more source
Scientists need to ask themselves if their meeting or conference is really necessary.
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Effect of Auditory Predictability on the Human Peripheral Auditory System
Auditory perception is facilitated by prior knowledge about the statistics of the acoustic environment. Predictions about upcoming auditory stimuli are processed at various stages along the human auditory pathway, including the cortex and midbrain ...
Lars Riecke +3 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source

