Results 81 to 90 of about 536,569 (368)
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva+1 more
wiley +1 more source
The Association Between Income and Life Expectancy in the United States, 2001-2014.
IMPORTANCE The relationship between income and life expectancy is well established but remains poorly understood. OBJECTIVES To measure the level, time trend, and geographic variability in the association between income and life expectancy and to ...
Rajendra Chetty+7 more
semanticscholar +1 more source
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze+3 more
wiley +1 more source
The S1025 peptide is the major antidote to the YrzI toxin, which we renamed here as SpyT (Small Peptide YrzI Toxin) and SpyA (Small Peptide YrzI Antitoxin) (1). Degradation of the toxin–antitoxin spyTA mRNA, either by a translation‐dependent cleavage by the endoribonuclease Rae1 (2) or by direct attack by 3′‐exoribonucleases (3), also contributes to ...
Laetitia Gilet+4 more
wiley +1 more source
Forecasting demand for long-term care based on multistate piecewise constant Markov process
This paper forecasts demand for long-term care based on multistate piecewise constant Markov process. Two types of data are mainly used in this study. The first type of data came from the Chinese Longitudinal Healthy Longevity Survey (CLHLS), 2008-2011.
Cui Xiaodong, Zheng Yuhua
doaj
A central limit theorem under sublinear expectations [PDF]
In this paper we consider a sequence of random variables with mean uncertainty in a sublinear expectation space. Without the hypothesis of identical distributions, we show a new central limit theorem under the sublinear expectations.
arxiv +1 more source
Key Points Question What is the association between sickle cell disease and life expectancy and lifetime income? Findings This cohort simulation modeling study showed that projected life expectancy (54 vs 76 years) and quality-adjusted life expectancy ...
D. Lubeck+8 more
semanticscholar +1 more source
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley +1 more source
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma+8 more
wiley +1 more source