Results 91 to 100 of about 320,450 (298)
The roles of computer self-efficacy, outcome expectancy, and attribution theory in impacting computer system use [PDF]
, 2001 TJte process by which individuals accept or reject information technologies was theoretically explained in a model employing attributional relationships and computer self-ejficacy and outcome expectancy.
Henry, John W., Stone, Robert W.
core
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
Discover EducationTeachers’ expectancy beliefs are strong predictors of successful curriculum implementation. Drawing from the expectancy-value theory (EVT) of achievement motivation, this study assessed teaching expectancy beliefs in curriculum implementation among ...
Edmond Kwesi Agormedah +3 more
doaj +1 more source
Expectation violations as an effective alternative to complex mentalizing in novel communication
iScienceSummary: Communicating without a shared language is often assumed to require cognitively demanding Theory of Mind reasoning. In this study, we tested whether a more parsimonious mechanism based on expectancy violations can achieve comparable performance.
Tatia Buidze +2 more
doaj +1 more source
User behaviors toward mobile video adoption in Taiwan: A qualitative study [PDF]
This study was designed to examine users' usage behaviors toward mobile video adoption in Taiwan. A modified UTAUT (Unified Theory of Acceptance and Use of Technology) model was designed to be the theory basis to develop questionnaires and open-ended ...
Lee, Jia-Ling
core
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
The Child is father of the man : implications for the demographic transition [PDF]
, 2009 We propose a new theory of the demographic transition based on the evidence that body development during childhood is an important predictor of adult life expectancy.
Croix, David de la +3 more
core
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source