Results 61 to 70 of about 43,438 (261)

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Belief Shift or Only Facilitation: How Semantic Expectancy Affects Processing of Speech Degraded by Background Noise

Frontiers in Psychology, 2018
Individuals use semantic expectancy – applying conceptual and linguistic knowledge to speech input – to improve the accuracy and speed of language comprehension.
Katherine M. Simeon, Klinton Bicknell, Tina M. Grieco-Calub, Tina M. Grieco-Calub   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Management of Employee Motivation within the Framework of Performance Appraisal System Based on Expectancy Theory [PDF]

فرایند مدیریت و توسعه
Purpose: This research aimed to apply expectancy theory in the employee performance appraisal system to improve the appraisal system and achieve operational solutions to motivate employees.
Hamidreza Alizadeh Tabar, Samad Barani Bonab, Mehdi Kheirandish, Mohammad Ataei   +3 more
doaj  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Nonverbal Expectancy Violation Theory: Esensi dan Perkembangannya

MediaTor, 2003
Setiap orang memiliki harapan tertentu pada perilaku nonverbal orang lain Jika harapan tersebut dilanggar, maka orang akan bereaksi dengan memberikan penilaian positif atau negatif sesuai karakteristik pelaku pelanggaran tersebut.
Antar Venus
doaj  

Business management teachers’ teaching expectancy beliefs about curriculum implementation: application of expectancy-value theory

Discover Education
Teachers’ expectancy beliefs are strong predictors of successful curriculum implementation. Drawing from the expectancy-value theory (EVT) of achievement motivation, this study assessed teaching expectancy beliefs in curriculum implementation among ...
Edmond Kwesi Agormedah, Leticia Bosu, Paul Tongkomah Saayir, Charles Omane-Adjekum   +3 more
doaj   +1 more source

Expectation violations as an effective alternative to complex mentalizing in novel communication

iScience
Summary: Communicating without a shared language is often assumed to require cognitively demanding Theory of Mind reasoning. In this study, we tested whether a more parsimonious mechanism based on expectancy violations can achieve comparable performance.
Tatia Buidze, Yuan-Wei Yao, Jan Gläscher   +2 more
doaj   +1 more source