Results 171 to 180 of about 603,582 (267)

Translation and initial psychometric evaluation of the Danish version of the treatment expectation questionnaire (TEX-Q). [PDF]

J Patient Rep Outcomes
Zachodnik J, Linding L, Thybo KH, Geisler A, Sandberg M.   +4 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Academic expectations stress, its associations with symptoms of depression and anxiety, and preliminary exploration of suicidality: results from a National Youth Mental Health Survey in Singapore. [PDF]

Front Psychol
Chua YC, Tang C, Tan B, Lee YP, Vaingankar JA, Chang S, Tan YWB, Samari E, Archana S, Ang RP, Subramaniam M, Verma SK.   +11 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Comparing Low and High Recovery Expectations Among Those with Lumbar Spinal Stenosis: A Network Analysis. [PDF]

Pain Med
Babitts A, Chen AT, Ehde DM, Goode AP, Jarvik JG, Cizik AM, Meier EN, Friedly JL, Horn ME, Suri P, Burke CA, Johnston SK, Rundell SD.   +12 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

The mediating role of basic psychological needs satisfaction in the link between parental expectations and competitive state anxiety among adolescent tennis players. [PDF]

Front Psychol
Zhang Z, Chen Z, Peng L.
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Generation Alpha's expectations at work: Well-being, pay and sense of agency. [PDF]

PLoS One
Syper-Jędrzejak M, Wojtaszczyk K, Mizera P, Różańska-Bińczyk I, Łuczak P.   +4 more
europepmc   +1 more source