Results 241 to 250 of about 3,596,779 (304)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Student satisfaction in transnational higher education in China: A mixed-methods study across Australian, German, and US cooperative programmes. [PDF]

PLoS One
Hu M.
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Reflections on Identity and Role Navigation of Continuous Medical Education Tutors in General Practice. [PDF]

Clin Teach
Keenan I, Barrett A, Duffy I, Byrne L, McNicholas C, Doran G, Dowling S.   +6 more
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Gendered digital housekeeping and invisible care labor in platformed higher education. [PDF]

Front Sociol
Li X, Cheah KSL, Wong YS.
europepmc   +1 more source

AI-enabled cardiovascular devices: a lifecycle playbook for evidence, change control, and post-market assurance. [PDF]

Front Digit Health
Ardic N, Dinc R.
europepmc   +1 more source

Relationship between expectations regarding aging and productive engagement among community-dwelling older adults: a cross-sectional study. [PDF]

Front Public Health
Dai S, Zhuo Y, Feng S, Zhao X, Qiao B, Wang J, Zhao M.   +6 more
europepmc   +1 more source

The dt-Report: A Novel Real-World Data Approach to Understanding the Use and Impact of Diabetes Technology in European Countries. [PDF]

J Diabetes Sci Technol
Brandt D, Hermanns N, Ehrmann D, Kulzer B, Diem P, Ampudia-Blasco J, Mader JK, Faber-Heinemann G, Heinemann L.   +8 more
europepmc   +1 more source