Results 91 to 100 of about 792,883 (326)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Rationality and dynamic consistency under risk and uncertainty [PDF]
, 2013 For choice with deterministic consequences, the standard rationality hypothesis is ordinality - i.e., maximization of a weak preference ordering. For choice under risk (resp.
Hammond, Peter J., Zank, Horst
core +2 more sources
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Is it best on the nest? Effects of avian life-history on haemosporidian parasitism
International Journal for Parasitology: Parasites and Wildlife, 2020 Infectious diseases vary in prevalence and pathology among host species. Species may differ in prevalence of infection due to varying exposure and susceptibility to disease agents throughout their lifetime, which may be attributable to underlying ...
Claudia Ganser +4 more
doaj +1 more source
Development of Interactive Support Systems for Multiobjective Decision Analysis under Uncertainty [PDF]
This paper presents interactive multiobjective decision analysis support systems, called MIDASS, which is a newly developed interactive computer program for strategic use of expected utility theory.
Fumiko Seo, Hidenobu Hamamoto
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Prospect Theory Goes to War: Loss-Aversion and the Duration of Military Combat [PDF]
, 1997 This paper contributes to the empirical foundation of prospect theory in real-life international relations by testing two of its major implications in the field of military conflict. Using duration analysis for a data set of twentieth century battles, it
Bauer, Thomas, Rotte, Ralph
core +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Journal of Modern and Contemporary Philosophy, 2020 Utility theory is the foundations of the marginalism that grounds neoclassical economics. From its inception, in the 1870’s, it’s been through many transformations: it began as hedonistic (Jevons), acquired ordinalist features (Pareto), radicalized by mid-twentieth century, reaquired some cardinalist properties (von Neumann and Morgenstern) and became ...
openaire +2 more sources
Contingent Claim Pricing In A Dual Expected Utility Theory Framework [PDF]
This paper investigates the price for contingent claims in a dual expected utility theory framework, the dual price, considering complete arbitrage-free nancial markets.
Andrea Gheno, Massimiliano Corradini
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