Results 81 to 90 of about 662,376 (305)

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

PENGARUH PEMBIAYAAN MODAL KERJA TERHADAP PENDAPATAN USAHA NASABAH PADA PT. BANK SYARIAH MANDIRI KANTOR CABANG SIMPANG PATAL PALEMBANG

open access: yesI-Finance, 2018
This study aims to investigate the Working Capital Financing Effect Against Revenue Customer At PT. Bank Syariah Mandiri Branch Office Simpang Patal Palembang.
Erdah Litriani
doaj   +1 more source

A simple test for the violation of the non-satiation axiom under uncertainty: The theory [PDF]

open access: yes
The validity of most axioms which underlie the expected utility model has been the object of intense empirical testing. These include the independence, betweenness, transitivity, monotonicity, reduction, and non-satiation axioms.
Calin Valsan, Robert Sproule
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Decreasing absolute risk aversion : some clarification [PDF]

open access: yes
La Vallée (1968), in the expected utility model, gives a sufficient condition for positivity of the bid-selling spread. In this article, we show that this sufficient condition, namely decreasing absolute risk aversion (DARA) is in fact necessary ...
Moez Abouda
core  

Prospect Theory Goes to War: Loss-Aversion and the Duration of Military Combat [PDF]

open access: yes, 1997
This paper contributes to the empirical foundation of prospect theory in real-life international relations by testing two of its major implications in the field of military conflict. Using duration analysis for a data set of twentieth century battles, it
Bauer, Thomas, Rotte, Ralph
core   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Development of Interactive Support Systems for Multiobjective Decision Analysis under Uncertainty [PDF]

open access: yes
This paper presents interactive multiobjective decision analysis support systems, called MIDASS, which is a newly developed interactive computer program for strategic use of expected utility theory.
Fumiko Seo, Hidenobu Hamamoto
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Is it best on the nest? Effects of avian life-history on haemosporidian parasitism

open access: yesInternational Journal for Parasitology: Parasites and Wildlife, 2020
Infectious diseases vary in prevalence and pathology among host species. Species may differ in prevalence of infection due to varying exposure and susceptibility to disease agents throughout their lifetime, which may be attributable to underlying ...
Claudia Ganser   +4 more
doaj   +1 more source

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