ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel +8 more
wiley +1 more source
Systematic Literature Review of the Economic and Quality of Life Burden of Congenital and Immune-Mediated Thrombotic Thrombocytopenic Purpura. [PDF]
Kaur H, Ghoshal D, Khurana IS.
europepmc +1 more source
CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang +6 more
wiley +1 more source
Cost-effectiveness analysis of sugemalimab plus chemotherapy for the first-line treatment of advanced gastric cancer or gastroesophageal junction cancer. [PDF]
Yan C, He J, Lv G, Gao Y, Li J, Diao R.
europepmc +1 more source
Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source
A harm-threshold model for ethical organ allocation. [PDF]
Lin YJ.
europepmc +1 more source
Can telemedicine help integrate the referral-based healthcare system? An economic and operational analysis. [PDF]
Cao X, Li G, Zhao H.
europepmc +1 more source
Validation of CURB-65, CRB-65, NEWS2, qSOFA, and 4C scores for predicting mortality in COVID-19 patients across seven emergency Departments in Colombia. [PDF]
Valderrama-Beltrán SL +22 more
europepmc +1 more source
External validation, recalibration, and clinical utility of the kidney failure risk equation in patients with advanced CKD: a nationwide retrospective cohort analysis in Peru. [PDF]
Bravo-Zúñiga JI +7 more
europepmc +1 more source
Modeling brain metastases in cost effectiveness analysis of atezolizumab for extensive stage small cell lung cancer. [PDF]
Chen HL +8 more
europepmc +1 more source

