Results 51 to 60 of about 1,453,138 (305)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
What Do We Know about Decision Making under Risk and Where Do We Go from Here?
Journal of Agricultural and Resource Economics, 1994 This article reviews two major approached used in the past for risk analysis - the expected utility approach and the use of safety rules and endeavors to reconcile their applicability and use in light of the recent nonexpected utility risk literature and
David E. Buschena, David Zilberman
doaj +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Representing risk preferences in expected utility based decision models [PDF]
Annals of Operations Research, 2008 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +3 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Modeling the Relationship between Expected Gain and Expected Value
Asia Marketing Journal, 2016 Rational choice theory holds that the alternative with largest expected utility in the choice set should always be chosen. However, it is often observed that an alternative with the largest expected utility is not always chosen while the choice task ...
Eugene J. S. Won
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Mean-Variance stochastic goal programming for sustainable mutual funds' portfolio selection.
Rect@, 2015 Mean-Variance Stochastic Goal Programming models (MV-SGP) provide satisficing investment solutions in uncertain contexts. In this work, an MV-SGP model is proposed for portfolio selection which includes goals with regards to traditional and sustainable ...
García-Bernabeu, Ana +3 more
doaj
Day-to-Day Evolution of Traffic Flow with Dynamic Rerouting in Degradable Transport Network
Journal of Advanced Transportation, 2019 Random events like accidents and vehicle breakdown, degrade link capacities and lead to uncertain travel environment. And whether travelers adjust route or not depends on the utility difference (dynamic rerouting behavior) rather than a constant ...
Manman Li, Jian Lu, Jiahui Sun, Qiang Tu
doaj +1 more source