Results 51 to 60 of about 912,632 (312)
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
The Fundamentals of Unemployment Compensation [PDF]
, 2019 [Excerpt] The joint federal-state Unemployment Compensation (UC) program provides income support through UC benefit payments. Although there are broad requirements under federal law regarding UC benefits and financing, the specifics are set out under ...
Isaacs, Katelin P, Whittaker, Julie M
core +1 more source
A Generalization of the Expenditure Function [PDF]
Journal of Optimization Theory and Applications, 2015 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
The impact of costs on the financial sustainability and efficiency of forestry enterprises
Agricultural and Resource EconomicsPurpose. The aim is to assess the impact of expenditures on the financial sustainability and efficiency of forestry enterprises and to develop scientifically based proposals that increase the transparency and reliability of cost accounting, as costs ...
Stanislav Vasylishyn +4 more
doaj +1 more source
MODEL OF RUSSIA ECONOMY REFORMATION ESTIMATION
Стратегические решения и риск-менеджмент, 2015 The topic origin suppositions are shown and investigation domain is appeared too. The economy scientific problem statement is derived and its state is analysed. The complex study apparatus is shown and modelling problem is formulated.
M. S. Krass
doaj +1 more source
Spatial Interdependence of Local Public Expenditures: Selected Evidence from the Czech Republic [PDF]
Local expenditures in neighbouring municipalities can be spatially interdependent due to spillovers, cooperation effects, competition effects or mimicking.
Lenka Šťastná
core +1 more source