Results 51 to 60 of about 1,611,195 (349)

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

The Effect of Tourist Expenses on Travellers' Satisfaction and Loyalty [PDF]

open access: yesAfrican Journal of Hospitality, Tourism and Leisure, 2020
This paper analyses the influence of tourist expenses on the satisfaction with Sarajevo as a tourist destination, as well as their loyalty. It observes how tourist expenses influence the general quality of tourist destination offer, overall tourist ...
Amra Čaušević   +3 more
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Interim results on concession agreements for the city of Perm and the Perm region

open access: yesВестник университета, 2023
The article focuses on the ongoing economic processes associated with the conclusion of concession agreements in Perm and the Perm Territory. It is noted that two dozen such agreements have been concluded over the past year.
E. V. Rozhkov
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Assessment of the effectiveness and prospects for the development of the activities of the Ukrainian Chamber of Commerce in conditions of environmental uncertainty [PDF]

open access: yesЕкономічний вісник Державного вищого навчального закладу Український державний хіміко-технологічний університет
Today, in an uncertain environment, enterprises, organizations, and citizens need to constantly improve their methods of activity by implementing and applying innovative measures.
O. M. Vinichenko   +2 more
doaj   +1 more source

Retirement Savings Accounts: Fees, Expenses, and Account Balances [PDF]

open access: yes, 2007
According to the U.S. Department of Labor, 43% of private-sector employees participated in defined contribution retirement plans, such as those authorized under §401(k) of the Internal Revenue Code, in March 2007.
Purcell, Patrick
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Comparative Analysis of the Major Points Under FAS Revenue, RAS 2/2008 Accounting for Construction Contracts, IFRS 15 Revenue on Contracts with Buyers and Recommendations for Refine the Draft Standard

open access: yesУчёт. Анализ. Аудит
The paper is relevant because it addresses the absence of regulatory documents for determining work completion and accounting revenue recognition in non-construction industries.
N. S. Suleymanov
doaj   +1 more source

Enterprises’ competitive behaviour assessment in industrial markets in manufacturing

open access: yesJournal of New Economy, 2020
Under the stagnating economy and turbulence in global and national markets, coun tries face a thorny question of establishing the strategic priorities of the state policy and maintaining sustainable growth of individual industrial companies.
N. Yu. Yaroshevich
doaj   +1 more source

Home - About - Disclaimer - Privacy