Results 51 to 60 of about 1,611,195 (349)
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
The Effect of Tourist Expenses on Travellers' Satisfaction and Loyalty [PDF]
This paper analyses the influence of tourist expenses on the satisfaction with Sarajevo as a tourist destination, as well as their loyalty. It observes how tourist expenses influence the general quality of tourist destination offer, overall tourist ...
Amra Čaušević +3 more
doaj +1 more source
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Interim results on concession agreements for the city of Perm and the Perm region
The article focuses on the ongoing economic processes associated with the conclusion of concession agreements in Perm and the Perm Territory. It is noted that two dozen such agreements have been concluded over the past year.
E. V. Rozhkov
doaj +1 more source
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Assessment of the effectiveness and prospects for the development of the activities of the Ukrainian Chamber of Commerce in conditions of environmental uncertainty [PDF]
Today, in an uncertain environment, enterprises, organizations, and citizens need to constantly improve their methods of activity by implementing and applying innovative measures.
O. M. Vinichenko +2 more
doaj +1 more source
Retirement Savings Accounts: Fees, Expenses, and Account Balances [PDF]
According to the U.S. Department of Labor, 43% of private-sector employees participated in defined contribution retirement plans, such as those authorized under §401(k) of the Internal Revenue Code, in March 2007.
Purcell, Patrick
core +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
The paper is relevant because it addresses the absence of regulatory documents for determining work completion and accounting revenue recognition in non-construction industries.
N. S. Suleymanov
doaj +1 more source
Enterprises’ competitive behaviour assessment in industrial markets in manufacturing
Under the stagnating economy and turbulence in global and national markets, coun tries face a thorny question of establishing the strategic priorities of the state policy and maintaining sustainable growth of individual industrial companies.
N. Yu. Yaroshevich
doaj +1 more source

