Results 121 to 130 of about 4,351,418 (319)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Advances in Experience Replay [PDF]

arXiv, 2018
This project combines recent advances in experience replay techniques, namely, Combined Experience Replay (CER), Prioritized Experience Replay (PER), and Hindsight Experience Replay (HER). We show the results of combinations of these techniques with DDPG and DQN methods. CER always adds the most recent experience to the batch.
arxiv  

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

History of Long-Baseline Accelerator Neutrino Experiments [PDF]

arXiv, 2019
I will discuss the six previous and present long-baseline neutrino experiments: two first-generation general experiments, K2K and MINOS, two specialized experiments, OPERA and ICARUS, and two second-generation general experiments, T2K and NOvA. The motivations for and goals of each experiment, the reasons for the choices that each experiment made, and ...
arxiv  

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Evaluating the Implementation of a Relationship-Centered Communication Training for Connecting With Patients in Virtual Visits

Journal of Patient Experience
The use of telehealth, specifically virtual visits, has increased and adoption continues. Providers need effective training for how to communicate with patients to develop a connection during virtual visits.
Rachyl Pines PhD, Marie C. Haverfield PhD, Stephanie Wong Chen MHA, Ethan Lee, Cati Brown-Johnson PhD, Merisa Kline MHA, Barbette Weimer-Elder RN, PhD   +6 more
doaj   +1 more source

Recovery among people with mental health challenges and alcohol and drug use issues in the Northern Territory, Australia

European Psychiatry
Introduction The Northern Territory (NT) has Australia’s highest mental health burden. It has a diverse and transient population, including Aboriginal and Torres Strait Islander people and various multicultural communities.
N. Tari-Keresztes, N. Armstrong, H. Gupta, J. A. Smith, S.-A. Endemann, S. Goding, J. Downes   +6 more
doaj   +1 more source

Recent experiences in the study and treatment of hysteria at the Massachusetts General Hospital; with remarks on Freud's method of treatment by "Psycho-analysis". [PDF]

, 1906
JAMES J. PUTNAM
openalex   +1 more source

Book review of “Here, there, everywhere—A memoir” by Peter Almond

, 2022
Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022.
Bruce J. Gerbi
wiley   +1 more source

Psychometric experiments. [PDF]

Brain, 1879
n ...
openaire   +4 more sources