Results 121 to 130 of about 3,635,984 (308)
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Long-distance exploration in insightful problem-solving
Insight represents a sudden and profound understanding, offering a new perspective that can offer the solution to a previously intractable problem. Insight is tightly associated with an “Aha” experience.
Zenas C. Chao +2 more
doaj +1 more source
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Minutes: Student Experiences Committee, February 28, 2022
University of Minnesota Duluth. Student Experiences Committee. (2022). Minutes: Student Experiences Committee, February 28, 2022.
University of Minnesota Duluth. Student Experiences Committee
core
Orientation: Globally, healthcare workplace environment is regarded as complex and interactive in nature, hence a supportive collegial environment is crucial in professional socialisation of newly qualified registered nurses, particularly (regulation ...
Tinyiko S. Baloyi +2 more
doaj +1 more source
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Minutes: Student Experiences Committee, April 15, 2019
University of Minnesota Duluth. Student Experiences Committee. (2019). Minutes: Student Experiences Committee, April 15, 2019.
University of Minnesota Duluth. Student Experiences Committee
core
Background: Maternal-related illnesses and pregnancy-related deaths could be averted using contraceptives, particularly long-acting methods because they improve overall access to family planning because of their benefits, such as fewer visits to the ...
Junior M. Ntimani, Moreoagae B. Randa
doaj +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source

