Results 81 to 90 of about 3,635,984 (308)

Conducting experiments with Experiment Manager [PDF]

open access: yesProceedings of the 28th conference on Winter simulation - WSC '96, 1996
This tutorial demonstrates how to conduct experiments and perform analysis with Experiment Manager, CACI's tool for design and analysis of simulation experiments. Experiment Manager works in conjunction with SIMPROCESS and provides a quick and object oriented approach to designing simulation experiments. The tutorial will describe how to conduct a full
openaire   +2 more sources

Quantifying Joystick Interactions and Movement Patterns of Toddlers With Disabilities Using Powered Mobility With an Instrumented Explorer Mini

open access: yesIEEE Transactions on Neural Systems and Rehabilitation Engineering
Powered mobility technology can be a powerful tool to facilitate self-initiated exploration and play for toddlers with motor disabilities. The joystick-controlled Permobil Explorer Mini is currently the only commercially available powered mobility device
Kimberly A. Ingraham   +9 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

On Experiments

open access: yesCoRR
The scientific process is a means to turn the results of experiments into knowledge about the world in which we live. Much research effort has been directed toward automating this process. To do this, one needs to formulate the scientific process in a precise mathematical language. This paper outlines one such language. What is presented here is hardly
openaire   +3 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

National dissemination of an online research mentor training intervention: Evidence of an asynchronous model to promote learning outcomes and behavior change

open access: yesJournal of Clinical and Translational Science
Engaging, accessible, evidence-based interventions are needed to support the professional development of research mentors within the clinical and translational sciences. This article reports on the usage and impact of the University of Minnesota Clinical
Anne Marie Weber-Main   +4 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

SOME EXPERIENCES WITH NEW EXPERIMENTS [PDF]

open access: yesSchool Science and Mathematics, 1904
n ...
openaire   +2 more sources

Den gröna slaktaren

open access: yesKulturella Perspektiv, 2001
Even in the older of industries: food production, there is a lot of talk about a new time, rapid changes and selling experiences instead of products. As an example of the new type of "value added products", the article examines the concept "The Green ...
Håkan Jönsson
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

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