Results 91 to 100 of about 99,989 (299)

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Experiential avoidance, self-efficacy, rejection sensitivity, and psychological symptoms in individuals with and without chronic illness

open access: yesKlinik Psikoloji Dergisi
The comorbidities of chronic physical illnesses and mental disorders are quite common, and the interaction of mental health issues with other health conditions indicates the need to examine psychological factors for effective intervention methods.
Yılmaz Orhun Gürlük, Gizem Gerdan
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Hospital staff experiences of their relationships with adults who self-harm: a meta-synthesis [PDF]

open access: yes, 2016
Purpose This review aimed to synthesize qualitative literature exploring inpatient hospital staff experiences of their relationships with people who self-harm.
Glover, Lesley, O'Connor, Sophie
core   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

open access: yesFEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Influence of school bullying on non-suicidal self-injury in adolescent with depressive disorder: a moderated mediation model

open access: yesSichuan jingshen weisheng
BackgroundSchool bullying is a serious social issue. Non-suicidal self-injury (NSSI) is a highly prevalent behavior among adolescents with depression and is also becoming a great matter of concern.
Meng Lingyu, Sun Zhenxiao
doaj   +1 more source

Do business games foster skills? A cross-cultural study from learners’ views [PDF]

open access: yes, 2018
Purpose: This study seeks to analyse students’ perception of the effectiveness of business games as an e-learning method in management training. This analysis of games’ effectiveness is centred in the generic and managerial skills acquired, through the ...
Fitó Bertran, Maria Àngels   +2 more
core   +4 more sources

Enzymatic and microbial routes to bioplastics: The green chemistry frontier of biopolymers

open access: yesFEBS Open Bio, EarlyView.
Microbial biosynthesis and engineered enzyme platforms are expanding the design space of polyhydroxyalkanoate bioplastics. By combining fermentation, PHA synthase engineering and cell‐free modular systems, tailored biodegradable polymers can be produced with tunable properties, supporting more sustainable materials and future circular bioeconomy ...
Giovanni Gallo   +4 more
wiley   +1 more source

The mediating role of the metacognition, time perspectives and experiential avoidance on the relationship between childhood trauma and post-traumatic stress disorder symptoms

open access: yesEuropean Journal of Psychotraumatology, 2019
Background: The current study was designed to investigate the direct and indirect effects of the childhood trauma, metacognition, time perspectives and experiential avoidance in prediction of post-traumatic stress disorder (PTSD) symptoms.
Nasrin Alsadat Hosseini Ramaghani   +4 more
doaj   +1 more source

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