Results 231 to 240 of about 9,267,633 (320)

A laboratory experiment demonstrating the dynamic character of membranes [PDF]

, 2000
Michael Eugene Pugh, Emeric Schultz
openalex   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Speech motor control is not sequestered from general auditory processes. [PDF]

J Exp Psychol Gen
Thorburn C, Zhou L, Dick F, Nozari N, Holt LL.   +4 more
europepmc   +1 more source

Assessment of waste rock weathering characteristics at the Antamina mine based on field cells experiment

, 2010
Celeldonio Aranda Clemente
openalex   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Effects of light pollution on development rate of the painted lady butterfly (Lepidoptera: Nymphalidae). [PDF]

Environ Entomol
Schultz JE, Gould GG.
europepmc   +1 more source

Experiments on fragmentation and thermo-chemical exchanges during planetary core formation

, 2017
Jean-Baptiste Wacheul, Michaël Le Bars
openalex   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Cognitive and emotional responses to viewing mummies in an Egyptian museum. [PDF]

Front Neurosci
Iosa M, Scaramozzino V, Benente M, Minucciani V, Franzò M.   +4 more
europepmc   +1 more source

Geochemical and petrographic evaluation of hydrous pyrolysis experiments on core plugs of Lower Toarcian Posidonia Shale: Comparison of artificial and natural thermal maturity series

Arysthasya Arysanto, Linda Burnaz, Tianyu Zheng, Ralf Littke   +3 more
openalex   +1 more source