Results 41 to 50 of about 2,477 (172)

Nerd Harder: A Typology of Techno‐Legal Solutionist Logics in Child Online Safety Laws

Policy &Internet, Volume 17, Issue 3, September 2025.
ABSTRACT As jurisdictions worldwide grapple with regulating social media's effects on youth, US state legislatures have emerged as important laboratories for “techno‐legal solutionism”—the belief that complex social problems can be solved through legally mandated technical fixes.
Amanda Reid, Lorcan Neill, Evan Ringel
wiley   +1 more source

Propuesta de incorporación de un eje temático de bienestar animal para el abordaje de un tema controversial: experimentación con animales [PDF]

, 2021
En los años como docente en la cátedra “Introducción a la Ciencia de los Animales de Laboratorio” en varias ocasiones escuché por parte de los estudiantes frases como “yo no voy a investigar con animales”, “no estoy de acuerdo con la investigación animal
Carranza Martín, Ana Cristina
core  

Dopamine D3 receptor blockade accelerates the extinction of opioid withdrawal‐induced drug‐seeking behaviours and alters microglia in dopaminoceptive nuclei

British Journal of Pharmacology, Volume 182, Issue 17, Page 4168-4185, September 2025.
Background and Purpose Among all drugs of abuse, opioids cause most of the deaths and treatment seeking. Despite abundant research in multifaceted therapeutic strategies, a high rate of relapse still characterises this condition. Dopamine D3 receptor antagonists combined with cue‐exposure therapies have been proposed to ameliorate the abused drugs ...
Aurelio Franco‐García, Victoria Gómez‐Murcia, M. Victoria Milanés, Cristina Núñez   +3 more
wiley   +1 more source

Adverse impact of acute Toxoplasma gondii infection on human spermatozoa

The FEBS Journal, Volume 292, Issue 17, Page 4720-4736, September 2025.
Toxoplasma gondii tachyzoites injected intraperitoneally crossed the blood‐testes barrier, appearing in testes/epididymis by day 6 post‐infection. In vitro exposure caused increased sperm necrosis/apoptosis and structural damage to heads/tails. Immunofluorescence and SEM revealed tachyzoites attaching to sperm tails, inducing twisting/detachment, and ...
Lisbeth Rojas‐Barón, Leandro Tana‐Hernandez, Mireille H. Nguele Ampama, Raúl Sanchéz, Ulrich Gärtner, Florian M. E. Wagenlehner, Christian Preußer, Elke Pogge von Strandmann, Carlos Hermosilla, Anja Taubert, María E. Francia, Zahady D. Velasquez   +11 more
wiley   +1 more source

The Impairment of Body Condition Transiently Increases Oxidative Stress: A Dietary Restriction Experiment in Partridges

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 343, Issue 7, Page 771-783, August 2025.
ABSTRACT A proper body condition determines the correct functioning of physiological processes and the optimal expression of fitness‐related traits. Among these processes, maintaining the redox balance is essential to protect the organism from damage caused by oxidative stress.
Nerea López‐Castañón, Silvia Casquero, Virginia Villanueva‐Santos, Lorenzo Pérez‐Rodríguez, Ana Ángela Romero‐Haro   +4 more
wiley   +1 more source

An adamantane‐based ligand as a novel chemical tool for thermosensory TRPM8 channel therapeutic modulation

The FEBS Journal, Volume 292, Issue 13, Page 3449-3476, July 2025.
Transient receptor potential cation channel subfamily M member 8 (TRPM8) is a cationic thermosensory channel crucial for cold sensation and menthol response. TRPM8 dysfunction leads to sensory symptoms such as cold allodynia. Targeting TRPM8 is important for treating diseases like peripheral neuropathies and cancer.
Angela Lamberti, Silvio Aprile, David Cabañero, Fabio Travagin, Laura Butron, Gregorio Fernández‐Ballester, Gian Cesare Tron, Asia Fernández‐Carvajal, Antonio Ferrer‐Montiel, Ubaldina Galli   +9 more
wiley   +1 more source

LINEAMIENTOS NORMATIVOS Y PRÁCTICOS PARA LA EXPERIMENTACIÓN ANIMAL EN COLOMBIA: COMITÉ DE ÉTICA, BIOÉTICA Y BIENESTAR ANIMAL DE LA UNIVERSIDAD DE LA AMAZONÍA

Revista de la Facultad de Ciencias Agropecuarias, 2019
El escrito desarrolla de manera detallada, mediante el uso de métodos analíticos y comparativos de información científica, algunos de los más relevantes argumentos y el marco normativo que fundamenta la experimentación animal en Colombia, con enfoque ...
Gloria Elena Estrada Cely
doaj  

Lessons from a Rubik's Cube to solve the biodiversity crisis

Conservation Biology, Volume 39, Issue 3, June 2025.
Abstract Global biodiversity is facing unprecedented pressures, calling into question the effectiveness of existing governance systems aimed at halting extinctions. Renewed hope arose with the recent Conference of the Parties (COP) to the Convention on Biological Diversity (COP15 December 2022) and the Convention on International Trade in Endangered ...
Ana M. M. Sequeira, Erika J. E. Techera
wiley   +1 more source

Determinación de la profundidad y duración de la neutropenia inducida por ciclofosfamida en ratones hembras MPF de la cepa Udea: ICR(cd-1)

Iatreia, 2004
<p>El modelo murino de infección del muslo emplea animales neutropénicos para poder determinar la eficacia intrínseca de los antibióticos in vivo. Sin embargo, no se ha definido el número de neutrófilos y la duración de la neutropenia inducida por ...
Omar Vesga, María Agudelo, Carlos Rodriguez, Andrés Zuluaga, Beatriz Salazar   +4 more
doaj  

Intrapopulational variation in head shape correlates with soil structure heterogeneity in a head‐first burrowing amphisbaenian, Trogonophis wiegmanni

Journal of Zoology, Volume 326, Issue 2, Page 130-139, June 2025.
Morphological traits evolve to solve ecological requirements. Amphisbaenians are fossorial reptiles with different snout shapes for burrowing head‐first underground, but how these head shapes have originated is little known. Here, using 2D geometric morphometrics, we found that individual Trogonophis wiegmanni amphisbaenians inside the same population ...
M. Kirchner, J. Ortega, R. García‐Roa, J. Müller, J. Martín   +4 more
wiley   +1 more source