Results 41 to 50 of about 9,477,480 (162)

Intratumoural tigilanol tiglate in the multicentre treatment of equine sarcoids and cutaneous melanomas

open access: yesEquine Veterinary Journal, Volume 58, Issue 1, Page 89-104, January 2026.
Abstract Background Intralesional chemotherapeutic administration represents an important treatment option for equine cutaneous neoplasia. Tigilanol‐tiglate (TT), a novel molecule extracted from Fontainea picrosperma, an Australian rainforest plant, is registered for intratumoural treatment of canine MCT, leading to rapid oncosis and tumour slough ...
Raphael Labens   +15 more
wiley   +1 more source

Redes discursivas en el debate sobre experimentación animal en prensa española sobre el caso Vivotecnia

open access: yesAthenea Digital
La experimentación con animales ha sido objeto de amplios debates políticos, sociales y científicos. En 2021, Cruelty Free International publicó vídeos que mostraban abusos a animales empleados para experimentación en el laboratorio Vivotecnia en la ...
Jose A. Moreno   +2 more
doaj   +1 more source

Evolving Platinum‐Copper Nanostructures for Enhanced Photothermal Therapy and Controlled Copper Release in Cancer Therapy

open access: yesAdvanced Functional Materials, Volume 35, Issue 52, December 23, 2025.
Platinum‐Copper bimetallic nanoparticles may evolve depending on their synthesis under tumor microenvironment conditions and play a dual role as chemotherapeutic agents after releasing Cu ions and as near infrared photothermal agents with the Pt‐rich remaining frames.
Jose I. Garcia‐Peiro   +7 more
wiley   +1 more source

High‐Phenolic Cocoa Enhances Drug‐Induced Reinstatement of Cocaine‐Conditioned Place Preference Independently of Increasing Adult Hippocampal Neurogenesis

open access: yesFood Science &Nutrition, Volume 13, Issue 9, September 2025.
High‐phenolic cocoa consumption enhanced cocaine‐induced reinstatement in a conditioned place preference paradigm. While cocoa promoted adult hippocampal neurogenesis, this effect did not mediate drug‐seeking behavior, suggesting a complex interaction between cocoa and cocaine on the reward system ABSTRACT Cocaine is a powerful psychostimulant that ...
Sonia Melgar‐Locatelli   +4 more
wiley   +1 more source

Modelo bioético personalista ontológico con fundamentación en la virtud para la experimentación con animales

open access: yes, 2014
El modelo bioético personalista con fundamentación en la virtud,con los principios del personalismo ontológico y las virtudes aristotélicas,es adecuado para la experimentación con animales por cuanto se trata de una actividad que realizan los seres ...
Garcés Giraldo, Luis Fernando
core   +1 more source

Teorías de ética animal: El debate actual

open access: yesDerecho Animal, 2015
Como consecuencia de los últimos descubrimientos científicos, discusiones muy estimulantes, han emergido en la escena científica nacional, respecto al uso de los animales en la experimentación y en la enseñanza.
Jéssica Lauren Steffen   +1 more
doaj   +1 more source

Dopamine D3 receptor blockade accelerates the extinction of opioid withdrawal‐induced drug‐seeking behaviours and alters microglia in dopaminoceptive nuclei

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 17, Page 4168-4185, September 2025.
Background and Purpose Among all drugs of abuse, opioids cause most of the deaths and treatment seeking. Despite abundant research in multifaceted therapeutic strategies, a high rate of relapse still characterises this condition. Dopamine D3 receptor antagonists combined with cue‐exposure therapies have been proposed to ameliorate the abused drugs ...
Aurelio Franco‐García   +3 more
wiley   +1 more source

Adverse impact of acute Toxoplasma gondii infection on human spermatozoa

open access: yesThe FEBS Journal, Volume 292, Issue 17, Page 4720-4736, September 2025.
Toxoplasma gondii tachyzoites injected intraperitoneally crossed the blood‐testes barrier, appearing in testes/epididymis by day 6 post‐infection. In vitro exposure caused increased sperm necrosis/apoptosis and structural damage to heads/tails. Immunofluorescence and SEM revealed tachyzoites attaching to sperm tails, inducing twisting/detachment, and ...
Lisbeth Rojas‐Barón   +11 more
wiley   +1 more source

Problemas bioéticos de la experimentación con animales no-humanos

open access: yes, 2021
La experimentación con animales es un tema polémico que cuenta con acérrimos defensores y detractores. Al ser un ámbito de la ciencia y de la técnica cuyo desarrollo, resultados y productos afectan a toda la sociedad, la denuncia sobre el problema moral ...
Leyton, Fabiola
core  

The Impairment of Body Condition Transiently Increases Oxidative Stress: A Dietary Restriction Experiment in Partridges

open access: yesJournal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 343, Issue 7, Page 771-783, August 2025.
ABSTRACT A proper body condition determines the correct functioning of physiological processes and the optimal expression of fitness‐related traits. Among these processes, maintaining the redox balance is essential to protect the organism from damage caused by oxidative stress.
Nerea López‐Castañón   +4 more
wiley   +1 more source

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