Results 111 to 120 of about 24,496,433 (332)
Editorial: Insights in veterinary experimental and diagnostic pathology: 2021
Frontiers in Veterinary Science, 2022 Francisco Javier Salguero
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EXPERIMENTAL ARTERIOSCLEROSIS [PDF]
Journal of Experimental Medicine, 1904 R M, Pearce, E M, Stanton
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Journal of Anthropological FilmsThe mountain of Tindaya (Fuerteventura, Canary Islands) has been entangled in controversy for over thirty years. The mountain is, at once, a sacred site for the indigenous people of Fuerteventura– who decorated it with hundreds of engravings–; a mining ...
Isaac Marrero Guillamón
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Revista de Medicina y Cine / Journal of Medicine and Movies, 2016 En África vive Lorenzo con sus padres, es un niño feliz. La familia marcha para Washington; allí pasados tres meses los profesores dicen que Lorenzo tiene un comportamiento problemático en el colegio, al que se va añadiendo caídas. En Semana Santa (1984)
Ana GARCÍA MENÉNDEZ
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Experimental quantum communication complexity
, 2005 We prove that the fidelity of two exemplary communication complexity protocols, allowing for an N-1 bit communication, can be exponentially improved by N-1 (unentangled) qubit communication.
A. C.-C. Yao +12 more
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source