Results 111 to 120 of about 25,744,716 (381)

EXPERIMENTAL ARTERIOSCLEROSIS [PDF]

open access: yesJournal of Experimental Medicine, 1904
R M, Pearce, E M, Stanton
openaire   +2 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Tindaya Variations

open access: yesJournal of Anthropological Films
The mountain of Tindaya (Fuerteventura, Canary Islands) has been entangled in controversy for over thirty years. The mountain is, at once, a sacred site for the indigenous people of Fuerteventura– who decorated it with hundreds of engravings–; a mining ...
Isaac Marrero Guillamón
doaj  

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

The UA9 experimental layout

open access: yes, 2011
The UA9 experimental equipment was installed in the CERN-SPS in March '09 with the aim of investigating crystal assisted collimation in coasting mode.
A Carnera   +67 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

El aceite de Lorenzo (Lorenzo´s Oil) (1992). Enfermedad: realidad mirada desde distintos puntos de vista

open access: yesRevista de Medicina y Cine / Journal of Medicine and Movies, 2016
En África vive Lorenzo con sus padres, es un niño feliz. La familia marcha para Washington; allí pasados tres meses los profesores dicen que Lorenzo tiene un comportamiento problemático en el colegio, al que se va añadiendo caídas. En Semana Santa (1984)
Ana GARCÍA MENÉNDEZ
doaj  

The Impact of the Quizlet App on Students' Mufradât Mastery: An Experimental Study

open access: yesAl-Ta'rib
This research is motivated by the observation that 10th-grade students at MAS Al-Huda in Gorontalo City have low mastery of mufradât. This is evident from their difficulties in understanding reading materials and communicating in Arabic.
Ibnu Rawandhy N. Hula   +5 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

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