Results 181 to 190 of about 24,496,433 (332)
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Histopathologic responses of the dental pulp to an experimental calcium aluminate-calcium silicate based capping material in comparison to mineral trioxide aggregate. [PDF]
Sci RepSaleh RS, Elbattawy EA, Hamza S, Aly Y.
europepmc +1 more source
Functional Classification and Experimental Dissection of Long Noncoding RNAs.
Cell, 2018 F. Kopp, J. Mendell
semanticscholar +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Revista Técnica de la Facultad de IngenieríaLos acondicionadores de aire por absorción se han comercializado en Venezuela en pequeña escala por más de treinta años. Existe un renovado interés por su uso como alternativa para la reducción en el consumo de electricidad residencial y desde el punto ...
Alejandro Colman +3 more
doaj
Exploring the chemical reactivity of 2,6-dimethylchromone toward heterocyclic hydrazines and enamines: experimental and theoretical investigations. [PDF]
RSC AdvAbdel-Megid M +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source