Results 241 to 250 of about 9,261,944 (317)

Effectiveness of a Web-Based Communication Education Program in Improving Knowledge and Self-Efficacy in Family Caregivers of Nursing Home Residents: A Quasi-Experimental Study. [PDF]

J Nurs Res
Hsiao CH, Chen YT, Shieh WY, Tsai HH.
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Flexural behaviour of RC shear wall using enhanced finite element model. [PDF]

Sci Rep
Nasr O, Moustafa A, Ghallab AH.
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

A Multispecies Systematic and Critical Review of Intranasal Administration in Veterinary Anaesthesia and Emergency Care: Promising Evidence and Overlooked Challenges. [PDF]

Vet Med Sci
Jafarbeglou M.
europepmc   +1 more source

Experimental Salmonellosiss

The KITAKANTO Medical Journal, 1962
openaire   +3 more sources

Assessment of fermented vegetable wastes in Nile tilapia diets: impacts on fish performance, amino acids profile, health, and intestine histomorphology. [PDF]

Sci Rep
Saleh NE, Sallam AE, Michael FR, Abdel-Mohsen HH, Almisherfi HM, Wassef EA.   +5 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Effects of Smoothened Agonist Exposure on Murine Craniofacial Development. [PDF]

Int Dent J
Mao C, Jiang Y, Li Z, Zhou W, Lai Y, Wang C, Lu M, Chen W.   +7 more
europepmc   +1 more source