Results 51 to 60 of about 9,261,944 (317)

Zoledronic acid effects interleukin-6 expression in hormone-independent prostate cancer cell lines

open access: yesInternational Brazilian Journal of Urology, 2008
OBJECTIVE: To investigate the inhibitory effects of zoledronic acid (ZA) on tumor related growth factor IL-6 in hormone resistant prostate cancer cell lines. The association between apoptosis and IL-6 inhibition was also assessed.
Layka A. Asbagh, Selim Uzunoglu, Cag Cal
doaj   +1 more source

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro   +11 more
wiley   +1 more source

Discourse Markers as Cues for Topic Shift Interpretation: Experimental Evidence from Spanish

open access: yesDiscours
Despite the complex terminological panorama regarding discourse markers (hereafter DMs) and the elusiveness of the notion of discourse topic, the relationship between these linguistic phenomena is a long-standing one.
Mercedes Villalobos Cardozo   +2 more
doaj   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

La propuesta de la Universidad Nómada: Una alternativa hacia la autoformación en la educación del arte

open access: yesINDEX Revista de Arte Contemporáneo, 2015
Este artículo examina cómo a partir del proceso de reestructuración académica del 2009 se entablan paradigmas, que en el Seminario: Arte y Educación (CAC, 2012), hacen que se evidencie y divulgue la opinión de los estudiantes respecto a diversas ...
Carlos Moreno   +4 more
doaj   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási   +14 more
wiley   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

Formas de paraboloides hiperbólicos en la arquitectura en Chile a mediados del siglo XX: materialización de la geometría en la escala del espacio

open access: yesInformes de la Construccion, 2023
El presente artículo es parte de nuestra investigación acerca del tema laminar de mediados del siglo XX en Chile, y se centra en obras y proyectos con paraboloides hiperbólicos poco estudiados pero que nuestra hipótesis valora al crear alternativas a ...
Branko Susa Mahuzier
doaj   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli   +3 more
wiley   +1 more source

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