Results 51 to 60 of about 9,261,944 (317)
Zoledronic acid effects interleukin-6 expression in hormone-independent prostate cancer cell lines
OBJECTIVE: To investigate the inhibitory effects of zoledronic acid (ZA) on tumor related growth factor IL-6 in hormone resistant prostate cancer cell lines. The association between apoptosis and IL-6 inhibition was also assessed.
Layka A. Asbagh, Selim Uzunoglu, Cag Cal
doaj +1 more source
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro +11 more
wiley +1 more source
Discourse Markers as Cues for Topic Shift Interpretation: Experimental Evidence from Spanish
Despite the complex terminological panorama regarding discourse markers (hereafter DMs) and the elusiveness of the notion of discourse topic, the relationship between these linguistic phenomena is a long-standing one.
Mercedes Villalobos Cardozo +2 more
doaj +1 more source
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke +4 more
wiley +1 more source
Este artículo examina cómo a partir del proceso de reestructuración académica del 2009 se entablan paradigmas, que en el Seminario: Arte y Educación (CAC, 2012), hacen que se evidencie y divulgue la opinión de los estudiantes respecto a diversas ...
Carlos Moreno +4 more
doaj +1 more source
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási +14 more
wiley +1 more source
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta +6 more
wiley +1 more source
El presente artículo es parte de nuestra investigación acerca del tema laminar de mediados del siglo XX en Chile, y se centra en obras y proyectos con paraboloides hiperbólicos poco estudiados pero que nuestra hipótesis valora al crear alternativas a ...
Branko Susa Mahuzier
doaj +1 more source
The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli +3 more
wiley +1 more source

