Results 51 to 60 of about 821,446 (263)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Low-cost chemical experiments: a contribution from the microscale

Revista Eureka sobre Enseñanza y Divulgación de las Ciencias, 2012
Experimental activities in laboratories are an important part in teaching and learning Chemistry. However, its implementation can normally be affected by a lack of materials, instruments, reagents price and the risks related to non-proper manipulation ...
González, Alexis, Urzúa, Carlos
doaj  

Engaging chemistry teachers with inquiry/investigatory based experimental modules for undergraduate chemistry laboratory education

Chemistry Teacher International
The experimental domain is central to chemistry education at undergraduate level. It is important that teachers teaching chemistry at this level are oriented with research informed approaches based on work done in chemistry education research. Currently,
Sen Indrani Das, Ladage Savita
doaj   +1 more source

Recent progress of porous geopolymers: nanoporosity regulation toward fundamental applications

Journal of Asian Ceramic Societies
Porous geopolymers have been the promising subject over the last decade owing to the functional domains from high surface area, structural stability upon heat and chemists, as well as eco-friendly and economy.
Hui-Yu Zhao, Gui-Lang Liu, Zhegang Huang, Long Yi Jin, Yi-Rong Pei   +4 more
doaj   +1 more source

Entendendo o processo químico de bioativação da sinvastatina por métodos experimentais e computacionais: uma aula prática

Química Nova, 2016
Cholesterol is a lipid which in high concentration can be an important risk factor for coronary diseases and atherosclerotic lesions. This lipid presents an endogenous biosynthesis that involves several steps; one of them is modulated by the enzyme 3 ...
Maurício Temotheo Tavares, Marina Candido Primi, Camila Felix de Carvalho, Michelle Carneiro Polli, Roberto Parise-Filho   +4 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Group discussions in secondary school chemistry: Unveiling pedagogical alchemy for academic advancement [PDF]

Journal of Pedagogical Research
Chemistry education in Rwandan secondary schools faces challenges, especially after the adoption of a competence-based curriculum that prioritizes student-centered learning. Traditional teacher-centered approaches often result in poor student performance.
Theophile Shyiramunda
doaj   +1 more source

Virtual experimental platforms in chemistry laboratory education and its impact on experimental self-efficacy

International Journal of Educational Technology in Higher Education, 2020
Self-efficacy is an important determinant in successfully attempting a task. In the area of education, self-efficacy plays a crucial role in causing behavioral changes, resulting in enhanced performance over the course of learning. In chemistry education,
Vysakh Kani Kolil, Sharanya Muthupalani, Krishnashree Achuthan   +2 more
doaj   +1 more source