Results 101 to 110 of about 8,299,755 (321)

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Adverse events after nivolumab and ipilimumab combined immunotherapy in advanced renal cell carcinoma: a multicentre experience in Poland

BMC Cancer
Background Immune checkpoint inhibitors (ICIs) have been employed in the adjuvant and metastatic setting of renal cell carcinoma (RCC) treatment. Among ICIs, combined immunotherapy has the highest risk for immune-related adverse events (irAEs).
Renata Pacholczak-Madej, Artur Drobniak, Łukasz Stokłosa, Anna Bidas, Jolanta Dobrzańska, Aleksandra Grela-Wojewoda, Agnieszka Roman, Daria Tusień-Małecka, Jerzy Walocha, Paweł Blecharz, Mirosława Puskulluoglu   +10 more
doaj   +1 more source

Investigation of Remaxol Efficacy in Complex Therapy of Experimental Generalized Tuberculosis on Mice

Антибиотики и Химиотерапия, 2020
Efficacy of remaxol In complex chemotherapy of generalized drug resistant tuberculosis was studied on mice. Mycobacterium tuberculosis 5419 SPBNIIF isolated from a patient with freshey diagnosticated pulmonary tuberculosis resistant to isoniazid (10 mcg ...
D. S. Sukhanov, T. I. Vinogradova, A. V. Elkin, N. V. Zabolotnykh, S. N. Vasilyeva, M. L. Vitovskaya   +5 more
doaj  

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

FEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang, Lynn Kee, Alexander Gont, Jalna Meens, Fraser G. Ferens, Meredith S. Irwin, Laurie Ailles, Scott A. Yuzwa, Claire M. Robinson, Michael Ohh   +9 more
wiley   +1 more source

Chemotherapy of Mice Experimentally Infected with Shigella flexneri [PDF]

, 1970
Naba Kumar Das, R. E. Chamberlain
openalex   +1 more source

EXPERIMENTAL TUBERCULOSIS AND ITS CHEMOTHERAPY [PDF]

British Journal of Pharmacology and Chemotherapy, 1950
Betty Croshaw, Lois Dickinson
openaire   +3 more sources

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

FEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori   +15 more
wiley   +1 more source

Experimental Study on Chemotherapy of Acute Glanders

Антибиотики и Химиотерапия, 2020
Glanders is a zoonotic infection inducing acute forms of the disease (pneumonia, sepsis) in humans and animals under certain conditions, which even with the use of modern chemotherapy have unfavourable prognosis.
V. I. Ilyukhin, K. A. Rotov, T. V. Senina, E. A. Snatenkov, S. N. Tikhonov, N. G. Plekhanova, A. S. Kulikova, E. V. Shubnikova, E. V. Korol, M. O. Nekhezina   +9 more
doaj  

Antiproteinase chemotherapy of acute experimental pancreatitis using the low molecular weight oligopeptide aldehyde leupeptin. [PDF]

, 1982
Peter A. Jones, John Hermon-Taylor, D. A. Grant   +2 more
openalex   +1 more source

Preclinical Monitoring of Drug Association in Experimental Chemotherapy of Chagas' Disease by a New HPLC-UV Method

Antimicrobial Agents and Chemotherapy, 2012
R. Moreira da Silva, Líliam Teixeira Oliveira, Neila Márcia Silva Barcellos, Jacqueline de Souza, M. de Lana   +4 more
semanticscholar   +1 more source