Results 11 to 20 of about 8,299,755 (321)

Experimental Chemotherapy-Induced Mucositis: A Scoping Review Guiding the Design of Suitable Preclinical Models. [PDF]

Int J Mol Sci, 2022
Mucositis is a common and most debilitating complication associated with the cytotoxicity of chemotherapy. The condition affects the entire alimentary canal from the mouth to the anus and has a significant clinical and economic impact.
Huang J, Hwang AYM, Jia Y, Kim B, Iskandar M, Mohammed AI, Cirillo N.   +6 more
europepmc   +2 more sources

Experimental Drugs for Chemotherapy- and Cancer-Related Anemia

Journal of Experimental Pharmacology, 2021
Clelia Madeddu,1 Manuela Neri,2 Elisabetta Sanna,2 Sara Oppi,3 Antonio Macciò2 1Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy; 2Department of Gynecologic Oncology, A. Businco Hospital, ARNAS G. Brotzu, Cagliari,
Madeddu C, Neri M, Sanna E, Oppi S, Macciò A   +4 more
doaj   +2 more sources

Atorvastatin and trans-caryophyllene for the prevention of leukopenia in an experimental chemotherapy model in Wistar rats. [PDF]

Mol Clin Oncol, 2015
Malignant neoplasia represents the second cause of disease-related mortality and, among all patients diagnosed with cancer, 70% will receive chemotherapy during the course of treatment.
Campos MI, Vieira WD, Campos CN, Aarestrup FM, Aarestrup BJ.   +4 more
europepmc   +2 more sources

Clofazimine shortens the duration of the first-line treatment regimen for experimental chemotherapy of tuberculosis. [PDF]

Proc Natl Acad Sci U S A, 2015
Tyagi S, Ammerman NC, Li SY, Adamson J, Converse PJ, Swanson RV, Almeida DV, Grosset JH.   +7 more
europepmc   +2 more sources

Experimental chemotherapy of tuberculosis. [PDF]

BMJ, 1968
John BATTENt
openaire   +4 more sources

Experimental Chemotherapy againstTrypanosoma cruziInfection Using Ruthenium Nitric Oxide Donors [PDF]

Antimicrobial Agents and Chemotherapy, 2009
Jean Jerley N. Silva, Wander Rogério Pavanelli, José Clayston Melo Pereira, João S. Silva, Douglas Wagner Franco   +4 more
openalex   +2 more sources

Experimental data-driven tumor modeling for chemotherapy

, 2020
Dániel András Drexler, Tamás Ferenci, András Füredi, Gergely Szakács, Levente Kovács   +4 more
openalex   +2 more sources

Glutathione Depletion Induced by c-Myc Downregulation Triggers Apoptosis on Treatment with Alkylating Agents

Neoplasia: An International Journal for Oncology Research, 2004
Here we investigate the mechanism(s) involved in the c-Myc-dependent drug response of melanoma cells. By using three M14-derived c-Myc low-expressing clones, we demonstrate that alkylating agents, cisplatin and melphalan, trigger apoptosis in the c-Myc ...
Annamaria Biroccio, Barbara Benassi, Francesco Fiorentino, Gabriella Zupi   +3 more
doaj   +1 more source

Phenotypic Evaluation of Nucleoside Analogues against Trypanosoma cruzi Infection: In Vitro and In Vivo Approaches

Molecules, 2022
Chagas disease, caused by Trypanosoma cruzi (T. cruzi), is a serious public health problem. Current treatment is restricted to two drugs, benznidazole and nifurtimox, displaying serious efficacy and safety drawbacks.
Ludmila F. de A. Fiuza, Denise G. J. Batista, Roberson D. Girão, Fabian Hulpia, Paula Finamore-Araújo, Mustafa M. Aldfer, Ehab Kotb Elmahallawy, Harry P. De Koning, Otacílio Moreira, Serge Van Calenbergh, Maria de Nazaré C. Soeiro   +10 more
doaj   +1 more source

TKI-addicted ROS1-rearranged cells are destined to survival or death by the intensity of ROS1 kinase activity

Scientific Reports, 2017
ROS1 rearrangement is observed in 1–2% of non-small cell lung cancers (NSCLC). The ROS1 tyrosine kinase inhibitor (TKI) crizotinib has induced marked tumour shrinkage in ROS1-rearranged cancers.
Hayato Ogura, Yuka Nagatake-Kobayashi, Jun Adachi, Takeshi Tomonaga, Naoya Fujita, Ryohei Katayama   +5 more
doaj   +1 more source