Results 281 to 290 of about 8,299,755 (321)
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Experimental Preoperative Chemotherapy
1986Preoperative adjuvant chemotherapy in experimental tumors is not new; more than 25 years ago Brock (1959) described the advantage of preoperative chemotherapy in a rat tumor (Table 1). The results were quite impressive, especially if these tumors were more than 10 g at the time of treatment. Not all tumors show a similar response and for that reason it
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Annals of Tropical Medicine and Parasitology, 1975
Three lines of Leishmania have been grown successfully in tissue culture. L. mexicana mexicana, L.tropica major and L. donovani develop readily as amastigotes in dog sarcoma cells, and in a hamster peritoneal exudate cell line.
N. Mattock, W. Peters
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Three lines of Leishmania have been grown successfully in tissue culture. L. mexicana mexicana, L.tropica major and L. donovani develop readily as amastigotes in dog sarcoma cells, and in a hamster peritoneal exudate cell line.
N. Mattock, W. Peters
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Experimental Cancer Chemotherapy
1954Publisher Summary Useful but not curative agents against cancer have been found. Steroids, carbamates, folic-acid analogs, nitrogen mustards, and related compounds are the most effective. While it can be anticipated that additional, active antifolic acids and nitrogen mustard-like compounds can be found, it is difficult to escape the impression that ...
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Interstitial chemotherapy of experimental gliomas
Cancer Treatment Reviews, 1990Two new approaches of interstitial (intratumoral) chemotherapy of gliomas are presented. Using s.c.-transplanted rat gliomas (G616) the therapeutic activity of biologically degradable polylactide rods as carriers for methotrexate was investigated. Carrier-mediated intratumoral chemotherapy was superior both to a systemic treatment and an intratumoral ...
Volker Sturm +5 more
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Annals of Tropical Medicine and Parasitology, 1975
A variety of compounds used in the treatment of parasitic or bacterial infections in man, including leishmaniasis itself, were examined for their activity against three lines of Leishmania in tissue culture. The organisms used were L.
N. Mattock, W. Peters
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A variety of compounds used in the treatment of parasitic or bacterial infections in man, including leishmaniasis itself, were examined for their activity against three lines of Leishmania in tissue culture. The organisms used were L.
N. Mattock, W. Peters
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Experimental Chemotherapy of Melanoma [PDF]
, 1984 Effective treatment of malignant melanoma represents a challenge for the experimental chemotherapist as well as the clinician. The response rates of disseminated or metastatic human melanoma to chemotherapy (either singly or in combination) are poor and average survival of patients is 6 months or less.
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Chemotherapy of Experimental Clostridial Infections
Journal of Infectious Diseases, 1952Recent events have increased the interest in the treatment of clostridial infections. During World War II a considerable amount of information was accumulated on the efficacy of sulfonamides (McKee et al, 1943; Hac and Hubert, 1944; Hac, 1944a; Langley and Winkelstein, 1945; Ryan et al, 1946) and of penicillin (McKee et al, 1943; Hac, 1944b; Macfarlane,
J. S. Kiser +3 more
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Experimental chemotherapy and toxicity in mice of three mebendazole polymorphic forms.
Chemotherapy, 1987In an attempt to test the biological activity of three polymorphic forms of mebendazole (MBZ), called A, B and C, both the LD50 in mice after oral (p.o.) and intraperitoneal (i.p.) administration and the anthelmintic effect of these forms on the enteral ...
F. Rodríguez-caabeiro +6 more
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Experimental Approaches to Antifungal Chemotherapy
1981Publisher Summary This chapter discusses the experimental approaches to antifungal chemotherapy. Fungal diseases in general occur in all parts of the world and affect all ages, though a number of particular species are restricted geographically in their incidence. It goes without saying that a systemic fungal infection will require systemic treatment.
Gravestock Mb +3 more
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, 1943
In previous studies (1) by exposure of mice to a standardized burn, a technique was developed whereby shock could be produced in a large number of animals in a short time.
S. Rosenthal
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In previous studies (1) by exposure of mice to a standardized burn, a technique was developed whereby shock could be produced in a large number of animals in a short time.
S. Rosenthal
semanticscholar +1 more source