Results 131 to 140 of about 13,287,487 (376)

Minimizing the linewidth of the Flux-Flow Oscillator

, 2007
For the first time the linewidth of Flux-Flow Oscillator has been calculated by direct computer simulation of the sine-Gordon equation with noise. Nearly perfect agreement of the numerical results with the formula derived in [Phys. Rev.
Pankratov, A. L.
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Probing Slepton Mass Non-Universality at e^+e^- Linear Colliders

, 2000
There are many models with non-universal soft SUSY breaking sfermion mass parameters at the grand unification scale. Even in the mSUGRA model scalar mass unification might occur at a scale closer to M_Planck, and renormalization effects would cause a ...
C. Kolda, Csaba Balázs, G. Blair, H. Baer, H. Baer, H. Baer, H. Baer, H. Baer, H. Baer, Howard Baer, I. Hinchliffe, J. Feng, J. Kenichi Mizukoshi, J. L. Feng, J. L. Feng, K. Agashe, M. Danielson, M. Drees, M. Schmaltz, M. Schmaltz, N. Arkani-Hamed, N. Polonsky, R. Barbieri, S. Choi, S. Choi, Stefan Hesselbach, T. Tsukamoto, Xerxes Tata   +27 more
core   +1 more source

Experimental Investigation of Cross Laminated Timber Elements with Holes or Notches at In-Plane Beam Loading Conditions [PDF]

, 2022
Mario Jeleč, Domagoj Damjanović, Damir Varevac, Vlatka Rajčić   +3 more
openalex   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Orchestrating distributed 5G edges for automotive cross-border trials: Validation of an experimental prototype [PDF]

, 2023
Nina Slamnik–Kriještorac, Mauro Femminella, Girma M. Yilma, Marco Liebsch, Gianluca Reali, Johann M. Márquez-Barja   +5 more
openalex   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Cultural Models of the Self and Environmentalism: A Cross-cultural and Experimental Investigation [PDF]

, 2020
Hamish Duff
openalex   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source