Results 251 to 260 of about 6,570,481 (314)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Plant-based protein extrusion optimization: Comparison between machine learning and conventional experimental design. [PDF]

Curr Res Food Sci
Jiang Y, Bin Noor Azlee NI, Ko WS, Chen K, Lim BG, Nelson AZ.   +5 more
europepmc   +1 more source

The sensitivity of expected utility violations to the experimental design : how context affects risky choice

, 2013
Michael J. Roberts
openalex   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

The effectiveness of Question Prompt Lists (QPL) in enhancing treatment outcomes for cancer patients among tribal population in Meghalaya: A quasi-experimental design. [PDF]

PLoS One
Dhar RR, Reshmi B, Holla R, Jaganathan V, Josten K, Mawlong A.   +5 more
europepmc   +1 more source

Design comparison of experimental stormwater detention systems

, 2005
Sara Kazemi Yazdi, H Nanbakhsh, Miklas Scholz   +2 more
openalex   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Internet-Delivered Psychological Treatment for Parents With Health Anxiety by Proxy: Replicated Randomized Single-Case Experimental Design. [PDF]

JMIR Form Res
Ingeman K, Frydendal DH, Frostholm L, Bjerre-Nielsen E, Wellnitz KB, Onghena P, Wright K, Rask CU.   +7 more
europepmc   +1 more source

Keratin Extraction Optimization from Poultry Feather Using  Response Surface- Box-Behnken Experimental Design Method

Ashagrie Mengistu Kebede, Ashagrie Mengistu Kebede, Getaneh Andualem, Mikiyas Abewaa Grano, Daniel Birhane   +4 more
openalex   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source