Results 111 to 120 of about 13,481,992 (294)
Methods of experimental reproduction of heart failure
Background. Cardiovascular diseases represent a significant medical and social problem, with heart failure being a common outcome. This condition contributes substantially to the rising rates of disability and mortality.
Dina S. Kuspanalieva +3 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Transcultural Insights into Contemporary Irish Literature and Society
Transcultural Insights into Contemporary Irish Literature and Society examines the transcultural patterns that have been enriching Irish literature since the twentieth century and engages with the ongoing dialogue between contemporary Irish literature ...
core +2 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
L’utilisation des échangeurs de chaleur air-sol (ECAS), pour le refroidissement des habitats connaît un développement important depuis quelques années. En zone sahélienne, la climatisation des habitats à partir des échangeurs de chaleur air-sol est une ...
B. Kaboré +4 more
doaj
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Cine experimental (1946). Cine hispanoargentino. Cine experimental. (11):195-195.
Cine experimental
core
Educational innovation is a key concept for policymakers, school leaders, and families, but its conflicting aspects make it hard to define clearly. This study explores how pro-innovation narratives are created within Spanish educational policies and how ...
Diego Luna +3 more
doaj +1 more source

