Results 111 to 120 of about 13,481,992 (294)

Methods of experimental reproduction of heart failure

open access: yesSiberian Journal of Life Sciences and Agriculture
Background. Cardiovascular diseases represent a significant medical and social problem, with heart failure being a common outcome. This condition contributes substantially to the rising rates of disability and mortality.
Dina S. Kuspanalieva   +3 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Transcultural Insights into Contemporary Irish Literature and Society

open access: yes
Transcultural Insights into Contemporary Irish Literature and Society examines the transcultural patterns that have been enriching Irish literature since the twentieth century and engages with the ongoing dialogue between contemporary Irish literature ...

core   +2 more sources

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Importación [PDF]

open access: yes, 1945
Cine experimental (1945). Importación. Cine experimental. (2):118-121.
Cine experimental
core  

Echangeur de chaleur air-sol à Ouagadougou: Revue de la littérature, étude analytique et expérimentation

open access: yesRevue des Énergies Renouvelables, 2017
L’utilisation des échangeurs de chaleur air-sol (ECAS), pour le refroidissement des habitats connaît un développement important depuis quelques années. En zone sahélienne, la climatisation des habitats à partir des échangeurs de chaleur air-sol est une ...
B. Kaboré   +4 more
doaj  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Cine hispanoargentino

open access: yes, 1946
Cine experimental (1946). Cine hispanoargentino. Cine experimental. (11):195-195.
Cine experimental
core  

“Inclination Towards Innovation”: Deconstructing Neoliberal Educational Discourses from a School Context

open access: yesSocieties
Educational innovation is a key concept for policymakers, school leaders, and families, but its conflicting aspects make it hard to define clearly. This study explores how pro-innovation narratives are created within Spanish educational policies and how ...
Diego Luna   +3 more
doaj   +1 more source

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