Results 81 to 90 of about 1,440,027 (252)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Medicine at theatre: a tool for well-being and health-care education

open access: yesBMC Medical Education
Effective communication plays a crucial role in healthcare settings, as it enhances patient outcomes and improves the overall quality of care and well-being.
Tessa Marzi   +5 more
doaj   +1 more source

Literature Research on Experimental Investigations of Automotive Turbocharger Rotordynamics

open access: yesActa Technica Jaurinensis, 2019
Contemporary turbochargers are high-speed rotating devices, commonly supported by full floating bearings or semi-floating bearings. Depending on the size and operational speed of the turbocharger, rotordynamics significantly changes.
Péter Sass
doaj   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

On Literature and the Experimental Forest Laboratory

open access: yesPublic Humanities
Abstract This article outlines the way in which the H.J. Andrews Experimental Forest Laboratory in Oregon has nurtured a conversation between writers, artists, and scientists. The Andrews was the birthplace of New Forestry, a concept and philosophy that has impacted writing on (and in) old-growth forests.
openaire   +1 more source

The record of experimental science: Archiving data with literature

open access: yesInformation Services and Use, 2010
Crystallography is presented as a case study of a scientific discipline where the experimental data that underpin research results can be integrated into the scientific record. Among other advantages, this maximises the degree of trust in science, since published results can thereby always be validated independently.
John R. Helliwell, Brian McMahon
openaire   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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