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Experimental models of epilepsy: A comprehensive review of mechanisms, translational relevance, and future directions. [PDF]
Jiji PJ +7 more
europepmc +1 more source
ECHS1: pathogenic mechanisms, experimental models, and emerging therapeutic strategies. [PDF]
Fu Q +10 more
europepmc +1 more source
Advances in modeling gastric intestinal metaplasia: a comprehensive review of experimental models and mechanistic insights. [PDF]
Liu X, Yang K, Zhang N, Sun X.
europepmc +1 more source
Evolution of the Experimental Models of Cholangiocarcinoma [PDF]
Cholangiocarcinoma (CCA) is a rare, aggressive disease with poor overall survival. In advanced cases, surgery is often not possible or fails; in addition, there is a lack of effective and specific therapies. Multidisciplinary approaches and advanced technologies have improved the knowledge of CCA molecular pathogenesis, highlighting its extreme ...
Massimo Aglietta +2 more
exaly +4 more sources
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Epileptogenesis in Experimental Models
Epilepsia, 2007Summary: Epileptogenesis refers to a phenomenon in which the brain undergoes molecular and cellular alterations after a brain‐damaging insult, which increase its excitability and eventually lead to the occurrence of recurrent spontaneous seizures. Common epileptogenic factors include traumatic brain injury (TBI), stroke, and cerebral infections.
Pitkänen, Asla +7 more
openaire +5 more sources
Experimental models of demyelination and remyelination
Experimental animal models constitute a useful tool to deepen our knowledge of central nervous system disorders. In the case of multiple sclerosis, however, there is no such specific model able to provide an overview of the disease; multiple models covering the different pathophysiological features of the disease are therefore necessary.We reviewed the
Ulises Gómez-Pinedo
exaly +4 more sources
Experimental Models of Dystonia
2011Dystonia is a disabling movement disorder characterized by involuntary, sustained muscle contractions, with repetitive twisting movements and abnormal postures. It is clinically classified as primary, either sporadic or genetic, or secondary, following focal brain lesions. The recent past has witnessed remarkable progress in finding genes for dystonia.
Tassone, A +4 more
openaire +3 more sources
Experimental Model of Varicocele
European Urology, 1989The purpose of this investigation was to create a varicocele model in animals and to study the subsequent alterations in testicular physiology. The study comprised 22 dogs divided into 2 groups: test and control. In the test group (17 dogs), excision of a longitudinal strip of the fasciomuscular tube of the spermatic cord was done on one side only.
A, Shafik +6 more
openaire +2 more sources

