Results 161 to 170 of about 10,600,838 (308)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

High-Precision Localization Algorithm for Target Symmetry Center in Image-Based Overlay Metrology. [PDF]

open access: yesMicromachines (Basel)
Liu W   +7 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Daily diet adjustments based on predefined group feeding curves: a practical and scalable approach to enhance nutrient efficiency and sustainability in pig production. [PDF]

open access: yesFront Vet Sci
Camargo NOT   +8 more
europepmc   +1 more source

Experimental Study of Hypernuclei Electroproduction by High Precision Spectroscopy [PDF]

open access: yes, 2009
Hiperjezgra se dobije zamjenom jednog ili više nukleona u jezgri s hiperonom, npr. s Λ, Σ ili Ξ. Budući da hiperon osim u i d kvarka ima i s kvark, Λ u nuklearni medij uvodi novi stupanj slobode - stranost. Zbog novog stupnja slobode Λ se razlikuje od nukleona zbog čega nema Paulijevog blokiranja što omogućuje proučavanje duboko vezanih stanja.
openaire   +3 more sources

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