Results 171 to 180 of about 5,472,250 (305)

Health Storylines Mobile Application and Self-management among Chronically Ill Patients: A Quasi-experimental Research Design. [PDF]

Acta Med Philipp
Moreno-Lacalle RC, Agbayani KPG, Alog JR, Antalan EPF, Aspiras RLAD, Astudillo PBS, Balbalin AE, Bogbog JPD, Bosque ILT, Carame AE, Cenizal MR, Corpuz RAR, Jacinto DA.   +12 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Experimental Research Progress on Gas-Liquid Flow and Heat Transfer Characteristics in Micro Pulsating Heat Pipes. [PDF]

Micromachines (Basel)
Chen J, Tian H, Xu W, Guo H, Wang C, Gu J, Cao Y.   +6 more
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Anales de la Estación Experimental de Aula Dei 21 (3). Especial 50 Aniversario.

, 1995
104 Pags. Índice: 1944-1994. La Estación Experimental de Aula Dei (CSIC): 50 años de investigación agraria / José Carlos Martínez Giménez y Enrique Fuertes Grábalos, pp. 117-132.-- Present and future trends in fruit research / S. Sansavini, pp.
CSIC - Estación Experimental de Aula Dei (EEAD)
core  

Experimental research on mechanical and microstructural characteristics of hybrid fiber reinforced concrete (HFRC). [PDF]

Sci Rep
Vadivel M, Selinaruby G, Padmapriya R, Perumal B.   +3 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Effect sizes for experimental research. [PDF]

Br J Math Stat Psychol
Hedges LV.
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Review of Long-Term Performance of Timber-Concrete Composite Beams

BioResources
Timber-concrete composite (TCC) beams are formed by integrating timber beams and concrete slabs into a cohesive structural unit using shear connectors.
Peiyang Liu, Hao Du, Zheng Chen, Xiamin Hu   +3 more
doaj