Results 251 to 260 of about 5,472,250 (305)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A multifaceted investigation into the impact of m6A methylation-related genes on pancreatic cancer, integrating insights from various databases and foundational experimental research. [PDF]

Ann Med Surg (Lond)
Wen Y, Liu Z, Chen Y.
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Cognitive Activity of an Individual Under Conditions of Information Influence of Different Modalities: Model and Experimental Research. [PDF]

Entropy (Basel)
Petukhov AY, Morozov NS, Krasnitskiy NV, Petukhov YV.   +3 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Comparative Study of Injected Alzheimer's Disease Models in Rats: Insights from Experimental Research. [PDF]

Pathophysiology
Doumar H, El Mostafi H, Elhessni A, Laaziz A, Mesfioui A.   +4 more
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Editorial: The current state of knowledge on asthma-COPD overlap (ACO) in clinical and experimental research: what do we know so far? [PDF]

Front Immunol
Degobbi Tenorio Quirino Dos Santos Lopes F, Tibério IFLC, Fraga Righetti R.   +2 more
europepmc   +1 more source

Experimental Research on Gradation Range and Performance of SMAC13. [PDF]

Materials (Basel)
Zhen Q, Cao W, Dong R, Liu S, Liu N, Zhan Z, Li Y.   +6 more
europepmc   +1 more source

An undergraduate experimental research program, involving the screening of efflux pump inhibitors, to improve student research skills in biomedical science. [PDF]

BMC Med Educ
Zong G, Zhang P, Wang Y, Han J, Wang L, Pan J, Pang J, Cao G, Fu J.   +8 more
europepmc   +1 more source