Results 241 to 250 of about 85,673,309 (349)

The Novel Object and Unusual Name (NOUN) Database: A collection of novel images for use in experimental research

Behavior Research Methods, 2016
Jessica S. Horst, Michael C. Hout
semanticscholar   +1 more source

Numerical simulation and experimental research on the oil removal efficiency during the oily wastewater separation by hydrocyclone. [PDF]

Sci Rep
Shuai Z, Weili Z, Laiyuan D, Dejun K, Wenwen Y.   +4 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Cocaine Cues Used in Experimental Research: A Systematic Review. [PDF]

Brain Sci
Brobbin E, Lowry N, Cella M, Copello A, Coulton S, Di Pietro J, Drummond C, Glautier S, Kiyak C, Phillips T, Stahl D, Starr S, Valmaggia L, Williams C, Deluca P.   +14 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Experimental Research on Quarry Wastewater Purification Using Flocculation Process. [PDF]

Molecules
Bu Y, Zeng K, Yang H, Sun A, Guan Q, Zhou S, Peng W, Wang W, Ge P, Yang Y.   +9 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Erratum for "The Impact of Care Delivered Through the Self-Management Promotion Model on Health Literacy Levels in Patients with Chronic Obstructive Pulmonary Disease: Quasi-Experimental Research". [PDF]

Health Lit Res Pract
europepmc   +1 more source

Experimental Research on and Optimization of Plasma Emitter Sources. [PDF]

Sensors (Basel)
Gao X, Zhou J, Du X.
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source