Results 131 to 140 of about 5,473,628 (305)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Experimental models for ovarian cancer research [PDF]

open access: yes, 2022
TSANG, SI, Hassan, AA, To, KY, Wong, AST
core   +1 more source

Experimental Archaeology and the tedious component in the experimental research process [PDF]

open access: yes
La Arqueología Experimental (AE) permite reconstruir procesos tecnológicos antiguos a través de la reproducción de técnicas y herramientas. Sin embargo, su comprensión suele estar teñida de un enfoque lúdico, donde las actividades replicativas se ...
Torres Navas, Concepción   +2 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Experimental Economics: Applications to Environmental Policy [PDF]

open access: yes
Incentives, regulations and other policy interventions intended to promote sustainability work through influencing human behaviour. There is therefore much to be gained from a thorough understanding of exactly how various policy interventions relate to ...
Andrew Reeson, Karel Nolles
core  

Applied Multivariate Research, v.13 no.2 (complete version) [PDF]

open access: yes, 2010
The second issue of Applied Multivariate Research edited by Dennis L. JacksonDigitized and published in SOAR:Shocker Open Access Repository by Wichita State University Libraries Technical Services.The effects of estimator choice and weighting strategies ...

core  

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

open access: yesFEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino   +2 more
wiley   +1 more source

Applied Multivariate Research, v.13 no.1 (complete version) [PDF]

open access: yes, 2009
The first issue of Applied Multivariate Research edited by Dennis L. JacksonDigitized and published in SOAR:Shocker Open Access Repository by Wichita State University Libraries Technical Services.Multivariate models for three dimensional data / James W ...

core  

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